Type: Chemotherapeutic agent
AKA: Vinblastine, Periwinkle
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III. Chemical Profile ( IUPAC name)
(3α,4α,5α,12α,19α)-3-Ethyl-9-((5-ethyl-5-hydroxy-6-methyl-2,4-dioxohexahydro-2H-pyran-3-yl)oxy)-12-(methoxycarbonyl)-2,3,3a,4,5,6,7,8,10,11,12,13,15,16,19,20-hexadecahydro-1H-indolizino[8,1-cd]carbazole-5-carboxylate
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IV. History
The Madagascar periwinkle has been used since the mid-20th century for its alkaloids vincristine and vinblastine, which are effective in cancer treatment.
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V. Legal Information
Vincristine and vinblastine are prescription medications used in chemotherapy.
Key US Federal Policies:
The FDA regulates vincristine and vinblastine as chemotherapeutic agents, ensuring they are prescribed and administered safely.
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VI. Physical Effects
Vincristine and vinblastine inhibit cell division by blocking the formation of microtubules, essential for cell division.
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VII. Psychological Effects
These substances do not have psychoactive effects. They are used to treat various types of cancer, including leukemia and lymphoma.
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VIII. Culture
The discovery of vincristine and vinblastine from periwinkle has had a major impact on chemotherapy protocols.
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