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Name: (Positional Isomer: 2,5-Dimethoxy-3,4dimethylphenethylamine (2C-G)) 4-methyl-alpha-ethylaminopentiophenone (4-MEAP)
Type:
AKA: 4-MEAP; 2-(ethylamino)-1-(4-methylphenyl)pentan-1-one)
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II. Natural Derivative
Synthetic substance, no natural derivative
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III. Chemical Profile (IUPAC name)
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IV. History
4-Methyl-alpha-ethylaminopentiophenone (4-MEAP) is a synthetic stimulant and a positional isomer of 2C-G. It belongs to the class of cathinones, substances that have effects similar to amphetamines. 4-MEAP has appeared on the recreational drug market and is used for its stimulant properties. Due to its potential for abuse and adverse effects, many countries have regulated or banned its use.
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V. Legal Information
2C-G and 4-Methyl-alpha-ethylaminopentiophenone (4-MEAP) are psychoactive substances with legal statuses varying by jurisdiction. 2C-G is often controlled as a Schedule I substance in the US due to its hallucinogenic effects. 4-MEAP may also be regulated under analog acts. Globally, both substances face increasing restrictions reflecting the trend towards strict controls on new psychoactive substances.
US Federal Schedule - I
Schedule I drugs, substances, or chemicals are defined as drugs with no currently accepted medical use and a high potential for abuse. Some examples of Schedule I drugs are: heroin, lysergic acid diethylamide (LSD), marijuana (cannabis), 3,4-methylenedioxymethamphetamine (ecstasy), methaqualone, and peyote.
Key US Federal Policies:
Controlled Substances Act. Public Law: Public Law 91-513 (text can be found on GovInfo) (https://www.dea.gov/drug-information/csa). Date enacted: October 27, 1970.
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VI. Physical Effects
2C-G and 4-MEAP are synthetic substances with hallucinogenic and stimulant effects. As uppers, they can cause increased heart rate, euphoria, and visual distortions. Short-term effects include altered perception, while long-term use may lead to psychological issues. Overdose risks involve severe agitation and psychosis. Safe use requires cautious dosing. Recent research highlights their hallucinogenic effects and the need for regulation due to potential abuse.  |
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VII. Psychological Effects
2C-G and 4-MEAP are psychoactive substances affecting serotonin and dopamine systems, leading to altered perception and mood. Psychological effects include hallucinations and euphoria, with risks of anxiety and psychosis. Effects last several hours, with ongoing research into their therapeutic potential and safety.
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VIII. Culture
4-Methyl-alpha-ethylaminopentiophenone (4-MEAP), a synthetic cathinone, is part of the broader phenomenon of 'bath salts' or 'legal highs' that gained attention in the early 21st century. Its cultural impact is tied to its use in recreational drug scenes, particularly among individuals seeking potent stimulant effects. The substance’s unpredictable and sometimes dangerous effects have made it a subject of public health concern. 4-MEAP reflects the challenges of regulating new psychoactive substances and the societal debates over drug safety and legal loopholes. Its role in the cultural narrative is one of caution and regulatory challenges.
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