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Name: -alpha-PHP; -alpha-pyrrolidinohexanophenone; 1-phenyl-2-(pyrrolidin-1-yl)hexan-1-one) alpha-pyrrolidinopentiophenone (-alpha-PVP)
Type:
AKA: alpha-pyrrolidinovalerophenone, 1-phenyl-2- (pyrrolidin-1-yl)pentan-1-one) (Positional Isomers: 4-methyl-alpha-pyrrolidinobutiophenone (4-MePBP), 1-phenyl-2-(piperidin-1-yl)butan-1-one)
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II. Natural Derivative
Synthetic substance, no natural derivative
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III. Chemical Profile (IUPAC name)
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IV. History
The first published description of the compound was in the Journal of the Chemical Society, and was a paper by Herrmann and Horner.
Herrmann and Horner's paper was followed by an article by Kuchler and Wilhelm.
A second paper by Kuchler and Wilhelm was published in the Journal of the Chemical Society in 1883.
It was published in German in the Journal of the Chemical Society, volume 13, pages 517-526.
It was published in English in the Journal of the Chemical Society, volume 16, pages 531-536.
The compound was named alpha pyrrolidinohexanophenone.
It was named alpha pyrrolidinohexanophenone.
Alpha pyrrolidinohexanophenone is a pyrrolidinohexanophenone.
Alpha pyrrolidinohexanophenone is a phenyl 2 (p
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V. Legal Information
Alpha-PHP (Alpha-Pyrrolidinohexanophenone) is a synthetic stimulant with similar effects to other cathinones. It is controlled due to its stimulant effects and potential for abuse, with global trends showing increasing regulation. [Source: UNODC].
US Federal Schedule - I
Schedule I drugs, substances, or chemicals are defined as drugs with no currently accepted medical use and a high potential for abuse. Some examples of Schedule I drugs are: heroin, lysergic acid diethylamide (LSD), marijuana (cannabis), 3,4-methylenedioxymethamphetamine (ecstasy), methaqualone, and peyote.
Key US Federal Policies:
Controlled Substances Act. Public Law: Public Law 91-513 (text can be found on GovInfo) (https://www.dea.gov/drug-information/csa). Date enacted: October 27, 1970.
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VI. Physical Effects
Alpha-PVP, a synthetic cathinone, emerged in the 2000s. It acts as an upper, leading to increased energy and euphoria. Physical impacts include elevated heart rate, dilated pupils, and increased blood pressure. Short-term use can cause agitation and paranoia, while long-term use may lead to severe psychological and cardiovascular issues. Overdose risks include severe agitation, hyperthermia, and cardiovascular distress. Safe use is challenging due to its high abuse potential. Recent research examines its stimulant effects and health risks.  |
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VII. Psychological Effects
A synthetic cathinone causing euphoria and increased energy. Long-term use can result in severe psychological effects such as paranoia, aggression, and cognitive decline. Research emphasizes its impact on neurotransmitter systems and associated mental health risks.
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VIII. Culture
Alpha-PHP is a synthetic stimulant causing increased energy and euphoria, classifying it as an upper. Short-term use induces heightened alertness and euphoria, while long-term use can lead to dependence and cardiovascular issues. Overdose risks include severe agitation, paranoia, and cardiovascular complications. Safe dosages are not well-established, with lower doses advised. Recent research highlights its abuse potential and health risks. Physical effects include increased heart rate, hypertension, and insomnia.
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