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Name: 2-(2,5-Dimethoxy-4-ethylphenyl) ethanamine (2C-E)
Type: Psychedelic phenethylamine
AKA: 2C-E (Positional Isomer: 2, 5-Dimethoxy-3, 4 dimethylphenethylamine (2C-G))
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II. Natural Derivative
Synthetic substance, no natural derivative
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III. Chemical Profile (IUPAC name)
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IV. History
2C-E, a member of the 2C family of psychedelic phenethylamines, was first synthesized in 1974 by Alexander Shulgin, a renowned chemist known for his work with psychoactive substances. Shulgin's research aimed to explore the potential of psychedelics for therapeutic use and altered states of consciousness. 2C-E became known for its powerful psychoactive effects, including visual hallucinations and altered perception. Initially used in controlled research and therapeutic settings, 2C-E eventually found its way into recreational use. Its legal status became a concern, leading to its classification as a controlled substance in several countries due to its high potential for abuse and health risks.
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V. Legal Information
2C-E is a psychedelic compound that is classified as a controlled substance in many jurisdictions due to its hallucinogenic properties. In the U.S., it is listed as a Schedule I drug under the Controlled Substances Act. Globally, its legal status varies, with many countries imposing strict controls due to its potential for abuse. The trend is towards increasing regulation in response to concerns about hallucinogen abuse. [Source: UNODC].
US Federal Schedule - I
Schedule I drugs, substances, or chemicals are defined as drugs with no currently accepted medical use and a high potential for abuse. Some examples of Schedule I drugs are: heroin, lysergic acid diethylamide (LSD), marijuana (cannabis), 3,4-methylenedioxymethamphetamine (ecstasy), methaqualone, and peyote.
Key US Federal Policies:
Controlled Substances Act. Public Law: Public Law 91-513 (text can be found on GovInfo) (https://www.dea.gov/drug-information/csa). Date enacted: October 27, 1970.
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VI. Physical Effects
2C-E is a psychedelic phenethylamine known for its hallucinogenic effects. It acts as an upper, causing alterations in perception and mood. Short-term use can produce intense visual and sensory effects, but long-term effects are not well understood. Overdose risks include severe psychological effects and potential physiological damage. Safe use involves cautious dosing and awareness of its potent effects. Recent research focuses on its pharmacology and therapeutic potential.  |
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VII. Psychological Effects
2C-E, a psychedelic phenethylamine, affects serotonin receptors, causing altered perception, euphoria, and cognitive changes. Immediate effects include vivid visual experiences and mood elevation. Long-term use may result in persistent psychological effects, including mood disorders and cognitive impairments. Recent studies highlight its potential for inducing intense psychological experiences and the associated risks of long-term use.
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VIII. Culture
2C-E is a psychedelic compound, classifying it as a hallucinogen. Short-term use induces altered perceptions and euphoria, while long-term effects are not well-documented. Overdose risks include severe psychological distress and potential for lasting mental health issues. Safe dosages are not well-established, with lower doses advised. Recent research focuses on its intense psychoactive effects and potential therapeutic uses. Physical effects may include dilated pupils, increased heart rate, and altered sensory perceptions.
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