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Name: 2-methyl AP-237 (1-(2-methyl-4-(3-phenylprop-2-en-1-yl)piperazin-1-yl)butan-1-one
Type: Synthetic opioid
AKA: N/A
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II. Natural Derivative
Synthetic substance, no natural derivative
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III. Chemical Profile (IUPAC name)
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IV. History
2-Methyl-AP-237, a synthetic stimulant, was developed in the 2010s. It reflects ongoing trends in stimulant research and development, with its use linked to both recreational and research contexts. Its history includes concerns about health risks and regulatory measures.
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V. Legal Information
2-Methyl AP-237, an opioid analgesic, is classified as a Schedule I controlled substance in the US, making it illegal. It is banned in many countries due to its high potential for abuse and overdose risks. The UNODC monitors synthetic opioids, emphasizing the need for international regulation to prevent misuse. Trends show increasing control measures to address the opioid crisis.
US Federal Schedule - I
Schedule I drugs, substances, or chemicals are defined as drugs with no currently accepted medical use and a high potential for abuse. Some examples of Schedule I drugs are: heroin, lysergic acid diethylamide (LSD), marijuana (cannabis), 3,4-methylenedioxymethamphetamine (ecstasy), methaqualone, and peyote.
Key US Federal Policies:
Controlled Substances Act. Public Law: Public Law 91-513 (text can be found on GovInfo) (https://www.dea.gov/drug-information/csa). Date enacted: October 27, 1970.
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VI. Physical Effects
2-Methyl-AP-237 is a synthetic stimulant with effects similar to amphetamines. It acts as an upper, increasing alertness and energy. Short-term use may enhance mood and physical performance, but long-term use poses risks of cardiovascular issues and psychological problems. Overdose risks include severe agitation and cardiovascular effects. Safe use requires cautious dosing. Recent research explores its stimulant effects and associated health risks.  |
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VII. Psychological Effects
2-Methyl AP-237 is a synthetic opioid analgesic producing euphoria, sedation, and pain relief. Immediate psychological impacts include mood elevation and cognitive impairment. Long-term use can lead to addiction, tolerance, and severe withdrawal symptoms. Chronic use is associated with depression, anxiety, and cognitive decline. Recent research emphasizes the high abuse potential and neurotoxicity of opioids.
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VIII. Culture
2-Methyl AP-237 is a synthetic opioid analgesic providing pain relief, classifying it as a downer. Short-term use alleviates severe pain, while long-term use can lead to dependence and tolerance. Overdose risks are high, causing respiratory depression and potentially fatal outcomes. Safe dosages are not well-established, with lower doses advised. Recent research underscores its potential for abuse and health risks. Physical effects include drowsiness, constricted pupils, and respiratory depression.
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