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Name: 3,4-Methylenedioxy-N-ethylamphetamine
Type: Psychedelic amphetamine (MDEA/Eve)
AKA: N-ethyl MDA, MDE, MDEA
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II. Natural Derivative
Synthetic substance, no natural derivative
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III. Chemical Profile (IUPAC name)
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IV. History
3,4-Methylenedioxy-N-Ethylamphetamine (commonly known as MDEA) was developed in the 1970s as a psychoactive substance. It is similar to MDMA and has been studied for its effects on mood and perception. It has been used recreationally and is part of the broader category of empathogens.
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V. Legal Information
3,4-Methylenedioxy-N-ethylamphetamine (MDEA) is a psychoactive compound with stimulant and empathogenic effects. It is controlled due to its potential for abuse and impact on mental health. [Source: UNODC].
US Federal Schedule - I
Schedule I drugs, substances, or chemicals are defined as drugs with no currently accepted medical use and a high potential for abuse. Some examples of Schedule I drugs are: heroin, lysergic acid diethylamide (LSD), marijuana (cannabis), 3,4-methylenedioxymethamphetamine (ecstasy), methaqualone, and peyote.
Key US Federal Policies:
Controlled Substances Act. Public Law: Public Law 91-513 (text can be found on GovInfo) (https://www.dea.gov/drug-information/csa). Date enacted: October 27, 1970.
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VI. Physical Effects
3,4-Methylenedioxy-N-ethylamphetamine (MDEA) is a psychoactive substance with both stimulant and empathogenic effects. It increases heart rate, blood pressure, and dilates pupils. Short-term use can enhance mood and emotional openness, while long-term use may lead to cognitive impairment and psychological issues. Overdose risks include severe agitation, cardiovascular problems, and potential death. Safe use requires careful dosing and controlled settings. Recent research highlights its mood-enhancing effects and risks of prolonged use.  |
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VII. Psychological Effects
3,4-Methylenedioxy-N-Ethylamphetamine (MDEA) is an empathogen-entactogen producing euphoria, increased sociability, and altered perception. Immediate effects include mood elevation and enhanced emotional experiences. Long-term use can lead to cognitive deficits, anxiety, and depression. Chronic use is associated with neurotoxicity and potential development of psychiatric disorders. Recent research highlights the risks of serotonin depletion and mood disturbances.
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VIII. Culture
3,4-Methylenedioxy-N-ethylamphetamine, commonly known as MDEA, is a synthetic empathogen. Its cultural significance is linked to its use in recreational settings and its effects on mood and social interaction. Media coverage often focuses on the risks and effects of empathogens and their role in recreational drug use. MDEA is used recreationally rather than medicinally and contributes to discussions about drug use and harm reduction.
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