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Name: 4-Methyl-2,5-dimethoxyamphetamine
Type: Psychedelic phenethylamine
AKA: DOM, STP
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II. Natural Derivative
Synthetic substance, no natural derivative
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III. Chemical Profile (IUPAC name)
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IV. History
4-Methyl-2,5-dimethoxyamphetamine (DOM), also known as STP, is a psychedelic amphetamine developed in the 1960s by Alexander Shulgin. It became infamous during the 1967 Summer of Love in San Francisco for its long-lasting and intense effects. Though never widely used, DOM remains a substance of interest in the study of psychedelics and their effects on human consciousness.
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V. Legal Information
4-Methyl-2,5-dimethoxyamphetamine (4-MDA) is a hallucinogenic compound regulated under international drug laws due to its psychoactive effects. It is classified as a Schedule I controlled substance in the US, reflecting its illegal status and potential for abuse. Globally, 4-MDA is similarly controlled under drug conventions and national laws. The regulatory trend focuses on preventing abuse while monitoring new psychoactive substances.
US Federal Schedule - I
Schedule I drugs, substances, or chemicals are defined as drugs with no currently accepted medical use and a high potential for abuse. Some examples of Schedule I drugs are: heroin, lysergic acid diethylamide (LSD), marijuana (cannabis), 3,4-methylenedioxymethamphetamine (ecstasy), methaqualone, and peyote.
Key US Federal Policies:
Controlled Substances Act. Public Law: Public Law 91-513 (text can be found on GovInfo) (https://www.dea.gov/drug-information/csa). Date enacted: October 27, 1970.
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VI. Physical Effects
4-Methyl-2,5-dimethoxyamphetamine (4-MDMA), a synthetic stimulant, acts as an upper with stimulant and empathogenic effects. Short-term effects include increased heart rate, euphoria, and dilated pupils, while long-term use may cause neurotoxicity and memory issues. Overdose risks include hyperthermia and serotonin syndrome. Safe dosage is not well established; recent research highlights concerns over neurotoxic effects and the need for caution due to high abuse potential.  |
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VII. Psychological Effects
4-Methyl-2,5-dimethoxyamphetamine (4-MDMA) influences serotonin systems, causing altered perception and mood. Effects last 6-8 hours, with potential for long-term cognitive and mood disturbances with frequent use. Current research investigates its impact on mental health and therapeutic uses in controlled settings.
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VIII. Culture
4-Methyl-2,5-dimethoxyamphetamine (DOM or STP) is a potent psychedelic that became popular in the 1960s counterculture. Known for its long-lasting effects, it was initially distributed as a recreational drug at music festivals and psychedelic gatherings. Its cultural impact is closely tied to the era’s experimentation with mind-altering substances, which aimed to expand consciousness and challenge societal norms. However, its unpredictability and the intensity of its effects led to numerous adverse reactions, causing concern among authorities and contributing to its eventual regulation. The substance remains a symbol of the 1960s' quest for expanded awareness and its associated risks.
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