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Name: 5F–ADB; 5F–MDMB–PINACA (Methyl 2-(1-(5-fluoropentyl)-1H-indazole-3-carboxamido)-3,3-dimethylbutanoate)
Type: Synthetic cannabinoid
AKA: 5F-ADB, 5F-MDMB-PINACA, (Positional isomer: 5F-AEB, 5F-EMB-PINACA), synthetic cannabinoids
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II. Natural Derivative
Synthetic substance, no natural derivative
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III. Chemical Profile (IUPAC name)
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IV. History
5F-ADB, also known as 5F-MDMB-PINACA, is a synthetic cannabinoid first synthesized in the 2010s. It was designed to mimic the effects of THC and interact with cannabinoid receptors. Its appearance in synthetic cannabis products reflects ongoing trends in synthetic cannabinoid development. 5F-ADB's high potency and health risks have led to increased regulatory scrutiny and control measures.
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V. Legal Information
5F-ADB and 5F-MDMB-PINACA, synthetic cannabinoids, are often regulated under analog laws due to their psychoactive effects. In the US, they might be controlled under the Federal Analog Act if deemed similar to other controlled substances. Globally, their status reflects efforts to manage novel psychoactive substances.
US Federal Schedule - I
Schedule I drugs, substances, or chemicals are defined as drugs with no currently accepted medical use and a high potential for abuse. Some examples of Schedule I drugs are: heroin, lysergic acid diethylamide (LSD), marijuana (cannabis), 3,4-methylenedioxymethamphetamine (ecstasy), methaqualone, and peyote.
Key US Federal Policies:
Controlled Substances Act. Public Law: Public Law 91-513 (text can be found on GovInfo) (https://www.dea.gov/drug-information/csa). Date enacted: October 27, 1970.
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VI. Physical Effects
5F-ADB and 5F-MDMB-PINACA are synthetic cannabinoids with potent psychoactive effects. They act as uppers, producing altered perception and euphoria. Short-term use can lead to intense psychological effects, while long-term effects are not well documented. Overdose risks include severe psychological distress and potential toxicity. Safe use is uncertain due to limited research. Recent studies focus on their effects and associated health risks.  |
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VII. Psychological Effects
5F-ADB and 5F-MDMB-PINACA, synthetic cannabinoids, affect cannabinoid receptors, leading to altered mood and perception. Immediate effects include euphoria and relaxation, with long-term use potentially causing anxiety and cognitive impairments. Research focuses on their potency and psychological impact.
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VIII. Culture
5F-ADB and 5F-MDMB-PINACA are synthetic cannabinoids with no historical lore but became known in the 21st century. Their cultural significance lies in their role as legal highs and the associated health risks. Proponents discuss their effects, while opponents highlight unpredictable effects and potential health dangers. Their use is primarily recreational, reflecting broader concerns about synthetic drug regulation.
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