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Name: 5F-PB-22 (Quinolin-8-yl 1-(5-fluoropentyl)-1H-indole-3-carboxylate)
Type: Synthetic cannabinoid
AKA: 5-Fluoro-PB-22; 5F-PB-22
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II. Natural Derivative
Synthetic substance, no natural derivative
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III. Chemical Profile (IUPAC name)
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IV. History
5F-PB-22 is a synthetic cannabinoid first identified in the 2010s. It is designed to mimic the effects of THC and has been found in recreational drug markets. 5F-PB-22 has been associated with severe adverse effects, including acute intoxication and fatalities. Its emergence has led to increased efforts to regulate synthetic cannabinoids and prevent their misuse.
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V. Legal Information
5F-PB-22 is a synthetic cannabinoid and is often regulated under analog laws due to its potent effects and potential for abuse. In the US, it is covered under the Federal Analog Act if deemed similar to controlled substances. Globally, its legal status is increasingly restrictive, reflecting efforts to control synthetic cannabinoids.
US Federal Schedule - I
Schedule I drugs, substances, or chemicals are defined as drugs with no currently accepted medical use and a high potential for abuse. Some examples of Schedule I drugs are: heroin, lysergic acid diethylamide (LSD), marijuana (cannabis), 3,4-methylenedioxymethamphetamine (ecstasy), methaqualone, and peyote.
Key US Federal Policies:
Controlled Substances Act. Public Law: Public Law 91-513 (text can be found on GovInfo) (https://www.dea.gov/drug-information/csa). Date enacted: October 27, 1970.
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VI. Physical Effects
5F-PB-22, a synthetic cannabinoid, is known for its potent psychoactive effects. As an upper, it causes intense euphoria and altered perception. Short-term effects include anxiety and paranoia, while long-term use may lead to severe mental health issues. Overdose risks involve acute psychosis and cardiovascular problems. Safe use is challenging due to potency variability. Recent research highlights its high potency and health risks, emphasizing the need for regulation.  |
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VII. Psychological Effects
5F-PB-22, a synthetic cannabinoid, affects the endocannabinoid system, causing altered mood and cognition. Psychological effects include euphoria, anxiety, and hallucinations. Effects last several hours, with risks of severe mental health issues and dependence. Research focuses on its safety profile and psychological impact.
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VIII. Culture
5F-PB-22 is a synthetic cannabinoid with effects similar to THC, classifying it as a downer. Short-term use induces euphoria and relaxation, while long-term use can lead to cognitive impairment and psychological dependence. Overdose risks include severe anxiety, hallucinations, and cardiovascular issues. Safe dosages are not well-established, with lower doses advised. Recent research highlights its high abuse potential and significant health risks. Physical effects include red eyes, dry mouth, and altered mental state.
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