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Name: AB-PINACA (N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-pentyl-1H-indazole-3-carboxamide)
Type: Synthetic cannabinoid
AKA: AB-PINACA, synthetic cannabinoids
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II. Natural Derivative
Synthetic substance, no natural derivative
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III. Chemical Profile (IUPAC name)
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IV. History
AB-PINACA, a synthetic cannabinoid, was first synthesized in the early 2010s. It was developed to interact with cannabinoid receptors and mimic the effects of THC. AB-PINACA became popular in synthetic cannabis products, leading to its widespread recreational use. The compound's potent effects and health risks have led to regulatory measures aimed at controlling its distribution and addressing the impact of synthetic cannabinoids on public health.
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V. Legal Information
AB-PINACA is a synthetic cannabinoid and is illegal in the US as a Schedule I substance. Globally, various countries have banned or restricted its use due to its potent psychoactive effects and health risks. Regulatory bodies like the UNODC have issued warnings about synthetic cannabinoids, leading to increased efforts to control these substances and mitigate their public health impacts.
US Federal Schedule - I
Schedule I drugs, substances, or chemicals are defined as drugs with no currently accepted medical use and a high potential for abuse. Some examples of Schedule I drugs are: heroin, lysergic acid diethylamide (LSD), marijuana (cannabis), 3,4-methylenedioxymethamphetamine (ecstasy), methaqualone, and peyote.
Key US Federal Policies:
Controlled Substances Act. Public Law: Public Law 91-513 (text can be found on GovInfo) (https://www.dea.gov/drug-information/csa). Date enacted: October 27, 1970.
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VI. Physical Effects
AB-PINACA is a synthetic cannabinoid with strong psychoactive effects. It acts as an upper, producing euphoria and altered perception. Short-term use can lead to intense effects, while long-term impacts are less understood. Overdose risks include severe psychological effects and potential toxicity. Safe use is uncertain due to limited research. Recent studies investigate its potency and potential health risks.  |
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VII. Psychological Effects
AB-PINACA, a synthetic cannabinoid, affects CB1 and CB2 receptors, leading to euphoria, altered perception, and relaxation. Immediate effects include mood elevation and sensory distortions, lasting several hours. Long-term use may result in severe psychological effects, including paranoia and cognitive impairments. Research highlights its high potency and associated risks of dependence and mental health issues.
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VIII. Culture
AB-PINACA is a synthetic cannabinoid with effects similar to THC, classifying it as a downer. Short-term use induces euphoria and relaxation, while long-term use can lead to cognitive impairment and psychological dependence. Overdose risks include severe anxiety, hallucinations, and cardiovascular issues. Safe dosages are not well-established, with lower doses advised. Recent research highlights its high abuse potential and significant health risks. Physical effects include red eyes, dry mouth, and altered mental state.
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