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Name: Alphaprodine
Type: Opioid analgesic
AKA: Nisentil
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II. Natural Derivative
Synthetic substance, no natural derivative
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III. Chemical Profile (IUPAC name)
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IV. History
Alphaprodine, also known as Prodine, is a synthetic opioid developed in the 1950s. It was used as an analgesic but fell out of favor due to its addictive properties and the development of more effective opioids. Its primary use was in pain management and surgical anesthesia.
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V. Legal Information
Alphaprodine, an opioid analgesic, is classified as a controlled substance due to its potential for abuse. Its legal status varies by country, focusing on its use in pain management and preventing misuse.
US Federal Schedule - II
Schedule II drugs, substances, or chemicals are defined as drugs with a high potential for abuse, with use potentially leading to severe psychological or physical dependence. These drugs are also considered dangerous. Some examples of Schedule II drugs are: combination products with less than 15 milligrams of hydrocodone per dosage unit (Vicodin), cocaine, methamphetamine, methadone, hydromorphone (Dilaudid), meperidine (Demerol), oxycodone (OxyContin), fentanyl, Dexedrine, Adderall, and Ritalin.
Key US Federal Policies:
Controlled Substances Act. Public Law: Public Law 91-513 (text can be found on GovInfo) (https://www.dea.gov/drug-information/csa). Date enacted: October 27, 1970.
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VI. Physical Effects
Alpha-prodine is a synthetic opioid used for pain relief. It causes sedation, respiratory depression, and constricted pupils, acting as a downer. Short-term use is effective for managing pain, but long-term use can lead to addiction, tolerance, and severe health issues. Overdose risks include fatal respiratory depression. Safe use requires strict dosing and medical supervision. Recent research highlights its potency and compares its risks with other opioids.  |
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VII. Psychological Effects
Alphaprodine, an opioid, affects opioid receptors, producing analgesia and mood enhancement. Immediate effects include euphoria and cognitive impairment, while long-term use may lead to dependence and psychological issues. Research examines its efficacy and potential for abuse.
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VIII. Culture
Alphaprodine, an opioid analgesic, has limited cultural significance. Developed in the mid-20th century, it was used primarily in medical settings. It has no historical lore or significant cultural impact beyond medical use. Modern references are scarce, and it is not widely known outside of specialist circles. Its cultural significance is minimal, primarily reflecting on the development and use of opioid medications in pain management. There are no significant proponents or opponents specifically associated with Alphaprodine.
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