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Name: Barbital
Type: Barbiturate
AKA: Veronal, Plexonal, barbitone
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II. Natural Derivative
Synthetic substance, no natural derivative
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III. Chemical Profile (IUPAC name)
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IV. History
Barbital, a barbiturate, was developed in the early 20th century and was used as a sedative and hypnotic. It has largely been replaced by newer medications due to its potential for addiction and overdose, but it remains a notable historical example of early sedative drugs.
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V. Legal Information
Barbital is a barbiturate used as a sedative and hypnotic. It is tightly controlled due to its potential for abuse and dependence. [Source: UNODC].
US Federal Schedule - IV
Schedule IV drugs, substances, or chemicals are defined as drugs with a low potential for abuse and low risk of dependence. Some examples of Schedule IV drugs are: Xanax, Soma, Darvon, Darvocet, Valium, Ativan, Talwin, Ambien, Tramadol.
Key US Federal Policies:
Controlled Substances Act. Public Law: Public Law 91-513 (text can be found on GovInfo) (https://www.dea.gov/drug-information/csa). Date enacted: October 27, 1970.
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VI. Physical Effects
Barbital is a barbiturate used for its sedative effects. It causes sedation, reduced heart rate, and constricted pupils. Short-term use provides effective sedation and anxiety relief, while long-term use can lead to dependence, cognitive impairment, and liver damage. Overdose risks include severe sedation and respiratory depression. Safe use involves careful dosing and monitoring. Recent research focuses on its historical use and current limitations due to side effects.  |
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VII. Psychological Effects
Barbital, a barbiturate, enhances GABA effects leading to sedation, anxiolysis, and muscle relaxation. Immediate effects include reduced anxiety, improved mood, and sedation. Long-term use can result in dependence, tolerance, and withdrawal symptoms. Chronic use is associated with cognitive impairment, depressive disorders, and increased anxiety. Recent studies indicate barbiturates can lead to structural changes in the brain.
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VIII. Culture
Barbital is a barbiturate used for sedation and anxiety, classifying it as a downer. Short-term use induces sedation and relaxation, while long-term use can lead to dependence, tolerance, and cognitive impairment. Overdose risks include severe sedation, respiratory depression, and potentially fatal outcomes. Safe dosages are typically prescribed by medical professionals. Recent research underscores its effectiveness in sedation but warns of high dependence and overdose risks. Physical effects include drowsiness, impaired coordination, and potential for respiratory depression.
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