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Name: Beta-hydroxy-3-methylfentanyl
Type: Synthetic opioid
AKA: China White, fentanyl
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II. Natural Derivative
Synthetic substance, no natural derivative
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III. Chemical Profile (IUPAC name)
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IV. History
Beta-Hydroxy-3-Methylfentanyl, a synthetic opioid, was developed in the 20th century as a potent analgesic. Its significance lies in its contributions to opioid research and the understanding of opioid receptor interactions for pain management.
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V. Legal Information
Beta-Hydroxy-3-methylfentanyl is a potent synthetic opioid regulated due to its high abuse potential. It is controlled under the Federal Analog Act in the U.S., with international controls reflecting efforts to address the opioid crisis and prevent misuse. [Source: UNODC].
US Federal Schedule - I
Schedule I drugs, substances, or chemicals are defined as drugs with no currently accepted medical use and a high potential for abuse. Some examples of Schedule I drugs are: heroin, lysergic acid diethylamide (LSD), marijuana (cannabis), 3,4-methylenedioxymethamphetamine (ecstasy), methaqualone, and peyote.
Key US Federal Policies:
Controlled Substances Act. Public Law: Public Law 91-513 (text can be found on GovInfo) (https://www.dea.gov/drug-information/csa). Date enacted: October 27, 1970.
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VI. Physical Effects
Beta-hydroxy-3-methylfentanyl is a potent synthetic opioid. It acts as a downer, causing significant sedation and respiratory depression. Short-term use is effective for pain management, but long-term use can lead to addiction and tolerance. Overdose risks include severe respiratory depression and potential death. Safe use requires precise dosing and medical supervision. Recent research examines its potency and potential health risks compared to other opioids.  |
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VII. Psychological Effects
Beta-hydroxy-3-methylfentanyl, a potent opioid, interacts with mu-opioid receptors, leading to strong euphoria and analgesia. Immediate effects include intense mood elevation and sedation, lasting several hours. Long-term use can result in severe addiction, cognitive impairments, and mood disorders. Research emphasizes its potency and the associated psychological risks of dependence and cognitive effects.
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VIII. Culture
Beta-hydroxy-3-methylfentanyl is a potent synthetic opioid, similar to fentanyl. Its cultural significance is closely tied to the opioid crisis and the challenges of managing potent synthetic opioids in public health. Media often covers the dangers of such substances and their role in overdose deaths. The substance is used recreationally rather than medicinally, contributing to societal conflicts about drug policy, harm reduction, and the regulation of synthetic opioids. Proponents of harm reduction advocate for safe consumption spaces and increased access to treatment, while opponents emphasize the need for stricter control and enforcement.
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