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Name: Clortermine
Type: Appetite suppressant
AKA: Voranil
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II. Natural Derivative
Synthetic substance, no natural derivative
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III. Chemical Profile (IUPAC name)
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IV. History
Clortermine, an appetite suppressant, was developed in the 1950s. It was used in the treatment of obesity but has since been withdrawn from the market due to safety concerns and the development of safer alternatives.
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V. Legal Information
Clortermine is a stimulant with anorectic effects. It is controlled due to its potential for abuse and impact on mental health, with regulations reflecting concerns about misuse. [Source: UNODC].
US Federal Schedule - III
Schedule III drugs, substances, or chemicals are defined as drugs with a moderate to low potential for physical and psychological dependence. Schedule III drugs abuse potential is less than Schedule I and Schedule II drugs but more than Schedule IV. Some examples of Schedule III drugs are: products containing less than 90 milligrams of codeine per dosage unit (Tylenol with codeine), ketamine, anabolic steroids, testosterone.
Key US Federal Policies:
Controlled Substances Act. Public Law: Public Law 91-513 (text can be found on GovInfo) (https://www.dea.gov/drug-information/csa). Date enacted: October 27, 1970.
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VI. Physical Effects
Clortermine is an appetite suppressant and stimulant. It causes increased heart rate, elevated blood pressure, and dilated pupils. Short-term use aids in weight loss, while long-term use may lead to cardiovascular issues and dependence. Overdose risks include severe cardiovascular effects and potential death. Safe use requires careful dosing and monitoring. Recent research highlights its efficacy for weight loss and associated cardiovascular risks.  |
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VII. Psychological Effects
Clortermine, a stimulant and appetite suppressant, affects neurotransmitter systems, including serotonin and norepinephrine. Immediate effects include increased alertness and mood elevation, lasting several hours. Long-term use may result in mood disturbances and cognitive impairments. Research highlights its impact on mood and cognition and the risks associated with chronic use, including potential for psychological dependence.
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VIII. Culture
Clortermine is an appetite suppressant used in the treatment of obesity. Its cultural significance is related to its role in weight management and obesity treatment. Media coverage often addresses the effectiveness and safety concerns associated with appetite suppressants. Clortermine is used medicinally and is part of broader discussions about obesity, weight loss treatments, and the balance between efficacy and safety in managing weight.
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