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Name: Codeine-N-oxide
Type: Opioid
AKA: N/A
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II. Natural Derivative
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IV. History
Codeine-N-oxide, a metabolite of codeine, was identified in the early 20th century. It is used in research to study opioid receptors and is part of the broader exploration of codeine's effects and derivatives.
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V. Legal Information
Codeine-N-oxide is a derivative of codeine with potential narcotic effects. It is controlled similarly to other opioids due to its abuse potential. In the United States, it is regulated under the Controlled Substances Act, and similar controls are enforced globally. [Source: UNODC].
US Federal Schedule - I
Schedule I drugs, substances, or chemicals are defined as drugs with no currently accepted medical use and a high potential for abuse. Some examples of Schedule I drugs are: heroin, lysergic acid diethylamide (LSD), marijuana (cannabis), 3,4-methylenedioxymethamphetamine (ecstasy), methaqualone, and peyote.
Key US Federal Policies:
Controlled Substances Act. Public Law: Public Law 91-513 (text can be found on GovInfo) (https://www.dea.gov/drug-information/csa). Date enacted: October 27, 1970.
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VI. Physical Effects
Codeine-N-oxide is a metabolite of codeine with potential analgesic effects. It may have similar effects to codeine but with different pharmacokinetics. Safe handling is crucial to avoid misuse. Short-term use may offer analgesic benefits, but long-term effects and safety profile are less well-studied. Recent research focuses on its role as a metabolite and potential clinical applications.  |
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VII. Psychological Effects
Codeine-N-oxide, a metabolite of codeine, has opioid-like effects including euphoria and sedation. Immediate effects include mood elevation and cognitive impairment. Long-term use can lead to dependence, tolerance, and withdrawal symptoms. Chronic use is associated with mood disorders and cognitive decline. Recent studies emphasize its abuse potential and risks similar to other opioids.
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VIII. Culture
Codeine-N-oxide, an opioid derivative, has no significant cultural lore but is documented in modern pharmacology. It is used for its analgesic effects, primarily in Western medicine. Its cultural impact includes discussions about opioid derivatives and their medical applications. There are no prominent proponents or opponents specifically associated with Codeine-N-oxide, but it is part of the broader context of opioid use and regulation. Its use is primarily medicinal, with no significant recreational use. It reflects ongoing debates about the safety and effectiveness of opioid medications.
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