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Name: Dextropropoxyphene dosage forms
Type: Opioid
AKA: Darvon, propoxyphene, Darvocet, Propacet
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II. Natural Derivative
Synthetic substance, no natural derivative
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III. Chemical Profile (IUPAC name)
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IV. History
Dextropropoxyphene, an opioid analgesic, was introduced in the 1950s for pain management. It was marketed in various dosage forms, including tablets and capsules, to treat mild to moderate pain. Despite its effectiveness, concerns about its safety and risk of overdose led to its withdrawal from the market in many countries. The FDA removed it from the US market in 2010 due to risks of serious toxicity. Its history reflects ongoing issues in balancing pain relief with the potential for opioid-related health risks.
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V. Legal Information
Dextropropoxyphene, an opioid used for pain relief, was once a controlled substance but has been withdrawn from the market in many countries due to safety concerns. Its status varies globally, with many jurisdictions now restricting or banning its use.
US Federal Schedule - IV
Schedule IV drugs, substances, or chemicals are defined as drugs with a low potential for abuse and low risk of dependence. Some examples of Schedule IV drugs are: Xanax, Soma, Darvon, Darvocet, Valium, Ativan, Talwin, Ambien, Tramadol.
Key US Federal Policies:
Controlled Substances Act. Public Law: Public Law 91-513 (text can be found on GovInfo) (https://www.dea.gov/drug-information/csa). Date enacted: October 27, 1970.
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VI. Physical Effects
Dextropropoxyphene is an opioid analgesic used for pain relief. It acts as a downer, causing sedation and respiratory depression. Short-term use is effective for pain management, but long-term use can lead to addiction, tolerance, and severe health issues. Overdose risks include fatal respiratory depression and heart problems. Safe use involves following prescribed dosages and monitoring for side effects. Recent research focuses on its efficacy and compares its risks with other opioids.  |
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VII. Psychological Effects
Dextropropoxyphene, an opioid, affects opioid receptors to provide analgesia and mood alteration. Immediate effects include euphoria and cognitive impairment, with long-term use carrying risks of dependence and mental health issues. Research examines its efficacy and potential for abuse.
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VIII. Culture
Dextropropoxyphene, an opioid pain medication, was widely used in the 20th century. It is mentioned in medical literature for its role in pain management. Its cultural impact includes debates over its safety and effectiveness, with concerns about its potential for abuse and overdose. Proponents valued its use in pain relief, while opponents highlight the risks associated with its use. Its use is primarily medicinal, reflecting broader issues in opioid treatment.
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