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Name: Drotebanol
Type: Opioid
AKA: Metebanyl, oxymethebanol
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II. Natural Derivative
Synthetic substance, no natural derivative
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III. Chemical Profile (IUPAC name)
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IV. History
Drotebanol, a synthetic opioid, was first synthesized in the 1970s. It was developed as a potent analgesic with applications in pain management. The compound's introduction to the medical field was part of broader research into opioid analgesics. Drotebanol's use has been associated with regulatory concerns due to its potential for abuse and dependence.
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V. Legal Information
Drotebanol, a synthetic opioid analgesic, is classified as a Schedule I controlled substance in the US, making it illegal. Many countries have similarly banned it due to its high potential for abuse and lack of accepted medical use. The UNODC monitors synthetic opioids, emphasizing the need for strict controls to prevent misuse and address the opioid crisis.
US Federal Schedule - I
Schedule I drugs, substances, or chemicals are defined as drugs with no currently accepted medical use and a high potential for abuse. Some examples of Schedule I drugs are: heroin, lysergic acid diethylamide (LSD), marijuana (cannabis), 3,4-methylenedioxymethamphetamine (ecstasy), methaqualone, and peyote.
Key US Federal Policies:
Controlled Substances Act. Public Law: Public Law 91-513 (text can be found on GovInfo) (https://www.dea.gov/drug-information/csa). Date enacted: October 27, 1970.
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VI. Physical Effects
Drotebanol is an opioid analgesic that acts as a depressant, inducing sedation and pain relief. It causes constricted pupils, slowed heart rate, and respiratory depression. Short-term effects include effective pain management, but long-term use may lead to addiction, tolerance, and respiratory issues. Overdose risks include severe respiratory depression and possible death. Safe use requires medical supervision. Recent research focuses on its pain management efficacy and addiction risks.  |
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VII. Psychological Effects
Drotebanol is an opioid with potent analgesic effects. Short-term use can lead to mood enhancement and sedation, while long-term use may cause addiction, cognitive impairments, and mood disorders. Research focuses on its impact on opioid receptors and psychological risks.
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VIII. Culture
Drotebanol is an opioid analgesic used for pain management. The history of opioids spans ancient medicinal use to modern pharmaceutical applications, with ongoing issues related to addiction and regulation. Drotebanol's cultural significance lies in its place within the broader narrative of opioid development, illustrating the complexities of balancing effective pain management with the risks of abuse and dependence. While not widely recognized in public discourse, it represents the ongoing challenges in opioid pharmacology and the pursuit of safer analgesic options. Media coverage typically focuses on more prominent opioids but highlights the broader context of opioid use and regulation.
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