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Name: Estazolam
Type: Benzodiazepine
AKA: ProSom, Domnamid, Eurodin, Nuctalon
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II. Natural Derivative
Synthetic substance, no natural derivative
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III. Chemical Profile (IUPAC name)
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IV. History
Estazolam, a benzodiazepine, was first developed in the 1970s. It was introduced for its anxiolytic and sedative effects. Estazolam's use has been associated with dependence and regulatory controls due to its potential for abuse.
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V. Legal Information
Estazolam, a benzodiazepine, is classified as a Schedule IV controlled substance in the US, allowing limited medical use. It is similarly regulated in many countries due to its potential for abuse and dependency. The UNODC emphasizes the need for balanced regulation to ensure safe medical use while preventing misuse. Trends indicate ongoing control measures to monitor and regulate benzodiazepines.
US Federal Schedule - IV
Schedule IV drugs, substances, or chemicals are defined as drugs with a low potential for abuse and low risk of dependence. Some examples of Schedule IV drugs are: Xanax, Soma, Darvon, Darvocet, Valium, Ativan, Talwin, Ambien, Tramadol.
Key US Federal Policies:
Controlled Substances Act. Public Law: Public Law 91-513 (text can be found on GovInfo) (https://www.dea.gov/drug-information/csa). Date enacted: October 27, 1970.
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VI. Physical Effects
Estazolam is a benzodiazepine used for its sedative and anxiolytic effects. It acts as a downer, causing sedation and reduced anxiety. Short-term use is effective for managing sleep disorders and anxiety, but long-term use may lead to dependence and cognitive impairment. Overdose risks include severe sedation and respiratory depression. Safe use requires precise dosing and medical supervision. Recent research explores its efficacy and associated risks.  |
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VII. Psychological Effects
Estazolam, a benzodiazepine, affects GABA receptors, leading to sedation and anxiety relief. Immediate effects include mood relaxation and reduced anxiety, lasting several hours. Long-term use can result in cognitive impairments, tolerance, and dependence. Recent studies highlight its efficacy in treating anxiety and associated risks of psychological dependence and cognitive effects.
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VIII. Culture
Estazolam, a benzodiazepine, is used for the short-term treatment of insomnia. Benzodiazepines have a long history of use in managing anxiety and sleep disorders, reflecting societal attitudes towards mental health and pharmaceutical intervention. In modern culture, they are both praised for their efficacy and criticized for their potential for dependence and abuse. Estazolam's role in sleep health underscores broader conversations about the balance between effective treatment and the risks of long-term medication use. Media discussions often highlight personal stories of dependence, contributing to ongoing debates about mental health treatment.
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