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Name: Etorphine (except HCl)
Type: Opioid
AKA: N/A
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II. Natural Derivative
Synthetic substance, no natural derivative
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III. Chemical Profile (IUPAC name)
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IV. History
Etorphine, a powerful synthetic opioid, was developed in the 1960s for veterinary use. It is significantly stronger than morphine and is used primarily to immobilize large animals such as elephants and rhinoceroses. Due to its potency, it is used with caution and under strict regulations. It has had a major impact on veterinary medicine by allowing for the safe and effective immobilization of large wildlife.
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V. Legal Information
Etorphine (excluding HCl) is a potent opioid used in veterinary medicine. It is controlled due to its high potency and potential for misuse, with stringent regulations in place. [Source: UNODC].
US Federal Schedule - I
Schedule I drugs, substances, or chemicals are defined as drugs with no currently accepted medical use and a high potential for abuse. Some examples of Schedule I drugs are: heroin, lysergic acid diethylamide (LSD), marijuana (cannabis), 3,4-methylenedioxymethamphetamine (ecstasy), methaqualone, and peyote.
Key US Federal Policies:
Controlled Substances Act. Public Law: Public Law 91-513 (text can be found on GovInfo) (https://www.dea.gov/drug-information/csa). Date enacted: October 27, 1970.
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VI. Physical Effects
Etorphine is a potent opioid used in veterinary medicine. It causes strong sedation, respiratory depression, and constricted pupils. Short-term effects include effective sedation and pain relief, while long-term use can lead to severe respiratory issues and addiction. Overdose risks are significant, with severe respiratory depression being a major concern. Safe use involves precise dosing and medical oversight. Recent research highlights its potency and the need for caution in its use.  |
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VII. Psychological Effects
Etorphine, a potent synthetic opioid, produces intense euphoria, sedation, and analgesia. Immediate psychological impacts include drowsiness, mood elevation, and cognitive impairment. Long-term use can lead to addiction, tolerance, and severe withdrawal symptoms. Chronic use is associated with depression, anxiety, and cognitive decline. Recent research emphasizes the high abuse potential and neurotoxicity of opioids.
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VIII. Culture
Etorphine is a potent opioid used primarily in veterinary medicine. It has no historical lore but became known in the late 20th century. Its cultural impact is related to its use in tranquilizing large animals and its potency compared to other opioids. Proponents highlight its effectiveness in veterinary care, while opponents caution about its potential misuse and safety. Its use is strictly medicinal, particularly in wildlife management.
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