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Name: Ezogabine
Type: Anticonvulsant
AKA: Potiga
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II. Natural Derivative
Synthetic substance, no natural derivative
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III. Chemical Profile (IUPAC name)
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IV. History
Ezogabine, an antiepileptic drug, was developed in the early 21st century. It is used to treat epilepsy and is known for its unique mechanism of action in modulating potassium channels.
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V. Legal Information
Ezogabine is an anticonvulsant used to treat epilepsy. It is regulated in various countries due to its potential side effects and dependence risk. In the United States, it is controlled under regulations for prescription medications, with similar controls globally. [Source: UNODC].
US Federal Schedule - V
Schedule V drugs, substances, or chemicals are defined as drugs with lower potential for abuse than Schedule IV and consist of preparations containing limited quantities of certain narcotics. Schedule V drugs are generally used for antidiarrheal, antitussive, and analgesic purposes. Some examples of Schedule V drugs are: cough preparations with less than 200 milligrams of codeine or per 100 milliliters (Robitussin AC), Lomotil, Motofen, Lyrica, Parepectolin.
Key US Federal Policies:
Controlled Substances Act. Public Law: Public Law 91-513 (text can be found on GovInfo) (https://www.dea.gov/drug-information/csa). Date enacted: October 27, 1970.
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VI. Physical Effects
Ezogabine is an anticonvulsant used to treat epilepsy. It causes sedation and may affect motor function. Short-term use is effective for managing seizures, while long-term use can lead to side effects such as urinary retention and cognitive impairment. Overdose risks include severe sedation and respiratory depression. Safe use involves following prescribed dosages and monitoring for side effects. Recent research focuses on its efficacy in treating epilepsy and safety profile.  |
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VII. Psychological Effects
Ezogabine, an antiepileptic, affects mood and cognition. Immediate effects include improved mood stabilization and reduced seizure frequency. Long-term use may result in cognitive impairment and potential mood disorders. Recent research highlights its efficacy in treating epilepsy but also emphasizes the risks of cognitive effects and mood changes associated with its use.
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VIII. Culture
Ezogabine is an anticonvulsant used to treat epilepsy, classifying it as a downer. Short-term use reduces seizure frequency, while long-term use can lead to vision problems and urinary retention. Overdose is rare but can cause severe drowsiness and confusion. Safe dosages are medically prescribed, typically starting at 100 mg three times daily. Recent findings focus on its effectiveness and potential side effects. Physical effects include drowsiness, dizziness, and potential retinal abnormalities.
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