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Name: Ganaxolone (3-alpha-hydroxy-3-beta-methyl-5-alpha-pregnan-20-one)
Type: Neurosteroid
AKA: N/A
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II. Natural Derivative
Synthetic substance, no natural derivative
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III. Chemical Profile (IUPAC name)
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IV. History
Ganaxolone, a synthetic neurosteroid, was developed in the 2010s for its anticonvulsant properties. It represents advancements in epilepsy treatment, providing a new option for managing seizures with a focus on efficacy and safety.
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V. Legal Information
Ganaxolone is a neuroactive steroid being studied for various therapeutic uses, including seizure disorders. Its legal status is evolving as it undergoes clinical trials. In the United States, it is not yet widely available but is subject to regulation by the FDA. Its use is monitored to ensure safety and prevent misuse. [Source: UNODC].
US Federal Schedule - V
Schedule V drugs, substances, or chemicals are defined as drugs with lower potential for abuse than Schedule IV and consist of preparations containing limited quantities of certain narcotics. Schedule V drugs are generally used for antidiarrheal, antitussive, and analgesic purposes. Some examples of Schedule V drugs are: cough preparations with less than 200 milligrams of codeine or per 100 milliliters (Robitussin AC), Lomotil, Motofen, Lyrica, Parepectolin.
Key US Federal Policies:
Controlled Substances Act. Public Law: Public Law 91-513 (text can be found on GovInfo) (https://www.dea.gov/drug-information/csa). Date enacted: October 27, 1970.
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VI. Physical Effects
Ganaxolone is a neuroactive steroid used to treat seizures and anxiety. It has sedative effects, reducing heart rate and causing drowsiness. Short-term use is effective for seizure and anxiety management, while long-term use is generally safe with minimal risk of dependency. Overdose risks are low, though excessive use may cause dizziness and impaired motor function. Safe use involves following prescribed dosages. Recent research supports its efficacy in treating seizures and anxiety, highlighting its safety profile.  |
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VII. Psychological Effects
Ganaxolone is a neurosteroid with anxiolytic and sedative effects. It may improve mood and reduce anxiety short-term, but long-term use could lead to dependence and cognitive effects. Recent research highlights its modulation of GABAergic systems and psychological impact.
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VIII. Culture
Ganaxolone is a synthetic steroid with potential therapeutic uses in treating epilepsy and other neurological conditions. Its cultural significance lies in its role in advancing treatment options for epilepsy. Media coverage often highlights its potential benefits and research developments. Ganaxolone is used medicinally and is part of broader discussions about neurological treatments and drug development.
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