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Name: Ginkgolides and Bilobalide
Type: Herbal supplement
AKA: Ginkgo, Maidenhair Tree
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II. Natural Derivative
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III. Chemical Profile (IUPAC name)
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IV. History
Ginkgolides and Bilobalide are compounds derived from the Ginkgo biloba plant, used in traditional medicine for their cognitive and circulatory benefits. Ginkgolides were first isolated in the 1980s, and Bilobalide was identified in the 1990s. These compounds are used as dietary supplements for their potential neuroprotective and antioxidant effects.
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V. Legal Information
Ginkgolides and Bilobalide, compounds derived from Ginkgo biloba, are not classified as controlled substances and are widely available as dietary supplements. They are not regulated under the Controlled Substances Act in the US. The UNODC does not monitor these compounds. Trends indicate ongoing use in traditional medicine and dietary supplements without significant legal restrictions.
Key US Federal Policies:
Ginkgo supplements are regulated by the FDA as dietary supplements. They must meet standards for labeling, purity, and safety.
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VI. Physical Effects
Ginkgolides and bilobalide, found in Ginkgo biloba, are used for cognitive enhancement and improving circulation. They generally cause mild gastrointestinal issues but have minimal adverse physical effects. They are not classified as stimulants or depressants. Short-term use is typically safe; however, excessive use may cause bleeding disorders. Safe doses range from 120-240 mg daily. Recent research highlights their benefits in cognition and circulation with minimal risks when used as directed.  |
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VII. Psychological Effects
Ginkgolides and bilobalide, compounds found in Ginkgo biloba, support cognitive function and mood regulation. Immediate effects include improved cognitive performance and mood. Long-term use is associated with reduced risk of cognitive decline and mood disorders. Research emphasizes their role in brain health and potential benefits for mental well-being, including cognitive enhancement and mood improvement.
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VIII. Culture
Ginkgolides and bilobalide are natural compounds found in Ginkgo biloba, a plant used in traditional medicine for thousands of years. Historically, Ginkgo biloba has been used in Chinese medicine for its supposed cognitive benefits and as a treatment for various ailments. In modern times, these compounds are studied for their potential neuroprotective effects and are marketed as dietary supplements for memory enhancement and cognitive health. The cultural significance of ginkgolides and bilobalide lies in their connection to traditional medicine and their role in the modern supplement industry, highlighting ongoing interests in natural health remedies and the integration of traditional knowledge with scientific research.
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