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Name: JWH-018 (also known as AM678) (1-Pentyl-3-(1naphthoyl)indole)
Type: Synthetic cannabinoid
AKA: JWH-018, AM-678, synthetic cannabinoids
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II. Natural Derivative
Synthetic substance, no natural derivative
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IV. History
JWH-018, also known as AM678, a synthetic cannabinoid, was first synthesized in the early 2000s. It is part of the JWH series and was developed to interact with cannabinoid receptors. The compound was included in synthetic cannabis products and gained popularity for its psychoactive effects. JWH-018's potency and health risks have led to regulatory measures.
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V. Legal Information
JWH-018, a synthetic cannabinoid, is classified as a Schedule I controlled substance in the US, making it illegal. Many countries have similarly banned it due to its potent psychoactive effects and health risks. The UNODC monitors synthetic cannabinoids, emphasizing the need for international regulation. Trends show increasing global control measures.
US Federal Schedule - I
Schedule I drugs, substances, or chemicals are defined as drugs with no currently accepted medical use and a high potential for abuse. Some examples of Schedule I drugs are: heroin, lysergic acid diethylamide (LSD), marijuana (cannabis), 3,4-methylenedioxymethamphetamine (ecstasy), methaqualone, and peyote.
Key US Federal Policies:
Controlled Substances Act. Public Law: Public Law 91-513 (text can be found on GovInfo) (https://www.dea.gov/drug-information/csa). Date enacted: October 27, 1970.
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VI. Physical Effects
JWH-018 is a synthetic cannabinoid with psychoactive effects. It acts as an upper, producing euphoria and altered perception. Short-term use can lead to intense effects, while long-term impacts are not well documented. Overdose risks include severe psychological effects and potential toxicity. Safe use is uncertain due to limited research. Recent studies focus on its psychoactive properties and health risks.  |
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VII. Psychological Effects
JWH-018, a synthetic cannabinoid, affects cannabinoid receptors, leading to euphoria, altered perception, and relaxation. Immediate effects include mood elevation and sensory distortions, lasting several hours. Long-term use may result in severe psychological effects, including paranoia and cognitive impairments. Research emphasizes its potential for psychological dependence and mental health risks.
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VIII. Culture
JWH-018, also known as AM-678, is a synthetic cannabinoid developed in the early 2000s. It has no historical or cultural lore but quickly became popular in the synthetic cannabinoid market. It is used recreationally for its psychoactive effects and is part of the legal high culture. Modern discussions focus on its safety, legality, and potential health risks. Proponents highlight its use as an alternative to cannabis, while opponents warn of its unpredictable effects and health dangers. Its cultural significance lies in the broader context of synthetic cannabinoids and the challenges of regulation.
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