|
Name: JWH-081 (1-Pentyl-3-(1-(4-methoxynaphthoyl)indole)
Type: Synthetic cannabinoid
AKA: JWH-081
|
|
II. Natural Derivative
Synthetic substance, no natural derivative
 |
|
|
IV. History
JWH-081, a synthetic cannabinoid, was first synthesized by John W. Huffman in 2006 at Clemson University. It was part of a series of compounds developed for research into cannabinoid receptors. Initially, it was used in laboratory settings to study the endocannabinoid system, but it soon appeared in the illicit drug market. By 2009, JWH-081 had become popular as a component of synthetic cannabis products, often sold as 'herbal incense.' The compound's legal status became a concern as many countries began to regulate synthetic cannabinoids due to their health risks and high potential for abuse. JWH-081 is known for its potent psychoactive effects, contributing to its widespread use and subsequent legal restrictions.
|
|
V. Legal Information
JWH-081, a synthetic cannabinoid, is often regulated under analog laws due to its psychoactive effects. In the US, it could fall under the Federal Analog Act if similar to other controlled substances. Globally, its status reflects efforts to manage novel psychoactive substances and prevent abuse.
US Federal Schedule - I
Schedule I drugs, substances, or chemicals are defined as drugs with no currently accepted medical use and a high potential for abuse. Some examples of Schedule I drugs are: heroin, lysergic acid diethylamide (LSD), marijuana (cannabis), 3,4-methylenedioxymethamphetamine (ecstasy), methaqualone, and peyote.
Key US Federal Policies:
Controlled Substances Act. Public Law: Public Law 91-513 (text can be found on GovInfo) (https://www.dea.gov/drug-information/csa). Date enacted: October 27, 1970.
|
|
VI. Physical Effects
JWH-081, a synthetic cannabinoid, produces potent psychoactive effects. As an upper, it induces euphoria and altered perception. Short-term effects include heightened sensory experiences, while long-term use can lead to psychological issues. Overdose risks include severe agitation and cardiovascular problems. Safe use involves cautious dosing, and recent research emphasizes its potency and potential for misuse.  |
|
VII. Psychological Effects
JWH-081, a synthetic cannabinoid, affects cannabinoid receptors, causing altered perception and mood changes. Immediate effects include euphoria and relaxation, with long-term use potentially leading to cognitive impairments and psychological issues. Research focuses on its potency and psychological effects.
 |
|
VIII. Culture
JWH-081 is a synthetic cannabinoid, classifying it as a downer. Short-term use induces relaxation and altered sensory perceptions, while long-term use can lead to dependence and cognitive impairment. Overdose risks include severe sedation, cognitive effects, and potential psychosis. Safe dosages are not well-established, with minimal use recommended. Recent research highlights its high potency and associated risks of cognitive effects. Physical effects include drowsiness, altered perceptions, and potential for impaired motor skills.
 |