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Name: JWH-250 (1-Pentyl-3-(2-methoxyphenylacetyl)indole)
Type: Synthetic cannabinoid
AKA: JWH-250, synthetic cannabinoids
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II. Natural Derivative
Synthetic substance, no natural derivative
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III. Chemical Profile (IUPAC name)
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IV. History
JWH-250, a synthetic cannabinoid, was first synthesized in the early 2000s. It is part of the JWH series, designed to interact with cannabinoid receptors. The compound's emergence in synthetic cannabis products reflects ongoing trends in synthetic drug development. JWH-250's potent effects and associated health risks have led to increased regulatory measures.
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V. Legal Information
JWH-250 is a synthetic cannabinoid with high abuse potential. It is controlled under the Federal Analog Act in the U.S. and faces increasing international regulation to prevent misuse. [Source: UNODC].
US Federal Schedule - I
Schedule I drugs, substances, or chemicals are defined as drugs with no currently accepted medical use and a high potential for abuse. Some examples of Schedule I drugs are: heroin, lysergic acid diethylamide (LSD), marijuana (cannabis), 3,4-methylenedioxymethamphetamine (ecstasy), methaqualone, and peyote.
Key US Federal Policies:
Controlled Substances Act. Public Law: Public Law 91-513 (text can be found on GovInfo) (https://www.dea.gov/drug-information/csa). Date enacted: October 27, 1970.
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VI. Physical Effects
JWH-250, a synthetic cannabinoid, was developed in the early 2000s. It acts as an upper, producing euphoria and altered perception. Physical impacts include increased heart rate, dilated pupils, and possible hypertension. Short-term use can lead to intense psychological effects and anxiety, while long-term use may result in dependence and cognitive issues. Overdose risks include severe psychological distress and potential toxicity. Safe use is uncertain due to limited research. Recent studies focus on its effects on cannabinoid receptors and associated health risks.  |
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VII. Psychological Effects
JWH-250, a synthetic cannabinoid, affects mood and perception. Immediate effects include euphoria and altered sensory experiences. Long-term use may lead to severe anxiety, psychosis, and cognitive impairments. Recent studies highlight its high abuse potential and significant psychological risks associated with synthetic cannabinoids.
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VIII. Culture
JWH-250, a synthetic cannabinoid, has no historical or cultural lore, being a recent development. It is used recreationally for its psychoactive effects and is part of the synthetic cannabinoid culture. Modern discussions focus on its safety and regulation, with proponents highlighting its effects as a legal high and opponents warning of its health risks. Its cultural significance lies in the broader context of synthetic cannabinoids and the challenges of regulating these substances. Its use is primarily recreational, with ongoing debates about its safety and legal status.
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