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Name: Lisdexamfetamine
Type: Stimulant
AKA: Vyvanse
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II. Natural Derivative
Synthetic substance, no natural derivative
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III. Chemical Profile (IUPAC name)
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IV. History
Lisdexamfetamine, a prodrug of dextroamphetamine, was developed in the 2000s for the treatment of ADHD and binge eating disorder. It was designed to provide a controlled release of dextroamphetamine to minimize abuse potential. Its introduction reflects advancements in ADHD treatment and its role in managing attention disorders with reduced risk of misuse.
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V. Legal Information
Lisdexamfetamine is a prescription stimulant used to treat ADHD and binge eating disorder. In the U.S., it is classified as a Schedule II controlled substance due to its abuse potential. Globally, its use is regulated to prevent misuse while allowing its medical application. Trends in regulation focus on balancing therapeutic use with prevention of abuse. [Source: UNODC].
US Federal Schedule - II
Schedule II drugs, substances, or chemicals are defined as drugs with a high potential for abuse, with use potentially leading to severe psychological or physical dependence. These drugs are also considered dangerous. Some examples of Schedule II drugs are: combination products with less than 15 milligrams of hydrocodone per dosage unit (Vicodin), cocaine, methamphetamine, methadone, hydromorphone (Dilaudid), meperidine (Demerol), oxycodone (OxyContin), fentanyl, Dexedrine, Adderall, and Ritalin.
Key US Federal Policies:
Controlled Substances Act. Public Law: Public Law 91-513 (text can be found on GovInfo) (https://www.dea.gov/drug-information/csa). Date enacted: October 27, 1970.
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VI. Physical Effects
Lisdexamfetamine is a stimulant used for treating ADHD. It acts as an upper, increasing focus and alertness. Short-term use can improve attention and reduce hyperactivity, but long-term use may lead to dependency and cardiovascular issues. Overdose risks include severe agitation and cardiovascular effects. Safe use requires careful dosing and medical supervision. Recent research supports its efficacy in treating ADHD while noting potential risks.  |
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VII. Psychological Effects
Lisdexamfetamine, a prodrug for dextroamphetamine, is used to treat ADHD. It enhances focus, mood, and cognitive function. Immediate effects include increased attention and mood improvement. Long-term use helps manage ADHD symptoms but may result in dependence and potential mood swings. Recent research supports its efficacy in treating ADHD with manageable psychological side effects.
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VIII. Culture
Lisdexamfetamine, marketed as Vyvanse, is a prescription medication used to treat ADHD and binge eating disorder. Its use reflects modern approaches to managing mental health and behavioral disorders. Historically, amphetamines have been used for various medical conditions, as well as recreationally for their stimulant effects. Lisdexamfetamine's introduction has spurred discussions about the medicalization of behavioral issues, the ethics of prescribing stimulants, and the balance between therapeutic benefits and the potential for misuse. Media often covers stories of success and controversy, highlighting the complexities of using stimulant medications in diverse populations.
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