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Name: MDMB–FUBINACA (Methyl 2-(1-(4-fluorobenzyl)-1H-indazole-3-carboxamido)-3,3-dimethylbutanoate)
Type: Synthetic cannabinoid
AKA: MDMB-FUBINACA (Positional Isomer: EMB-FUBINACA)
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II. Natural Derivative
Synthetic substance, no natural derivative
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III. Chemical Profile (IUPAC name)
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IV. History
MDMB-FUBINACA, a synthetic cannabinoid, was first synthesized in the 2010s. It is known for its potent effects and was developed as part of a broader trend in synthetic cannabinoids. MDMB-FUBINACA's appearance in synthetic cannabis products has been associated with increased health risks, leading to regulatory scrutiny and control measures.
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V. Legal Information
MDMB-Fubinaca is a synthetic cannabinoid often regulated under analog acts or specific bans due to its potent effects and potential for abuse. In the US, it is covered under the Federal Analog Act if deemed similar to controlled substances. Globally, its legal status varies, with increasing restrictions reflecting concerns about synthetic cannabinoids and their impact on public health.
US Federal Schedule - I
Schedule I drugs, substances, or chemicals are defined as drugs with no currently accepted medical use and a high potential for abuse. Some examples of Schedule I drugs are: heroin, lysergic acid diethylamide (LSD), marijuana (cannabis), 3,4-methylenedioxymethamphetamine (ecstasy), methaqualone, and peyote.
Key US Federal Policies:
Controlled Substances Act. Public Law: Public Law 91-513 (text can be found on GovInfo) (https://www.dea.gov/drug-information/csa). Date enacted: October 27, 1970.
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VI. Physical Effects
MDMB-Fubinaca, a synthetic cannabinoid, is known for its potent psychoactive effects. As an upper, it causes intense euphoria and altered perception, with increased heart rate and dilated pupils. Short-term effects include anxiety and paranoia, while long-term use can lead to severe mental health issues and addiction. Overdose risks involve acute psychosis and cardiovascular problems. Safe use is challenging due to potency variability. Recent findings emphasize the need for regulation and caution due to high health risks and potential for severe adverse effects.  |
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VII. Psychological Effects
MDMB-Fubinaca, a synthetic cannabinoid, affects the endocannabinoid system, leading to altered mood and cognition. Psychological effects include euphoria, anxiety, and hallucinations. Effects last several hours, with risks of severe mental health issues and dependence. Research focuses on its safety profile and impact on mental health.
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VIII. Culture
MDMB-Fubinaca is a synthetic cannabinoid with no historical or cultural lore, emerging in the early 21st century. Its cultural significance lies in its use as a legal high and the associated health and legal challenges. Proponents of synthetic cannabinoids highlight their effects and legal status in certain regions, while opponents warn of health risks and unpredictable effects. Its use is primarily recreational, reflecting broader issues in synthetic drug regulation and public health.
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