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Name: Mecloqualone
Type: Sedative-hypnotic
AKA: Nubarene
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II. Natural Derivative
Synthetic substance, no natural derivative
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III. Chemical Profile (IUPAC name)
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IV. History
Mecloqualone, a sedative and anxiolytic, was developed in the 1960s. It was used for its calming effects but has since been largely discontinued due to concerns about addiction and safety. It remains a part of the historical development of sedative medications.
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V. Legal Information
Mecloqualone is a sedative with potential for abuse. It is controlled under sedative laws due to its effects on mental health and potential for addiction. [Source: UNODC].
US Federal Schedule - I
Schedule I drugs, substances, or chemicals are defined as drugs with no currently accepted medical use and a high potential for abuse. Some examples of Schedule I drugs are: heroin, lysergic acid diethylamide (LSD), marijuana (cannabis), 3,4-methylenedioxymethamphetamine (ecstasy), methaqualone, and peyote.
Key US Federal Policies:
Controlled Substances Act. Public Law: Public Law 91-513 (text can be found on GovInfo) (https://www.dea.gov/drug-information/csa). Date enacted: October 27, 1970.
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VI. Physical Effects
Mecloqualone is a sedative-hypnotic with anxiolytic and muscle relaxant properties. It causes sedation, decreased heart rate, and dilated pupils. Short-term use helps with sleep disorders, but long-term use may lead to dependence and cognitive impairment. Overdose risks include severe sedation, respiratory depression, and potential death. Safe use involves strict dosing guidelines. Recent research focuses on its sedative effects and associated risks of prolonged use.  |
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VII. Psychological Effects
Mecloqualone, a sedative, affects GABA receptors, leading to relaxation and drowsiness. Immediate effects include mood enhancement and sedation, lasting several hours. Long-term use may result in cognitive impairments, dependence, and mood disturbances. Research emphasizes its sedative properties and associated risks of cognitive effects and psychological dependence.
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VIII. Culture
Mecloqualone is a sedative with hypnotic effects, used historically for sleep disorders. Its cultural significance is related to its role in the history of sedative treatments and the associated risks of misuse. Media coverage often focuses on the challenges of managing sedatives and their impact on health. Mecloqualone is used medicinally and is part of broader discussions about sleep disorders and sedative treatments.
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