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Name: Meprobamate
Type: Sedative
AKA: Miltown, Equanil, Micrainin, Equagesic, Meprospan
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II. Natural Derivative
Synthetic substance, no natural derivative
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III. Chemical Profile (IUPAC name)
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IV. History
Meprobamate, introduced in the 1950s, is an anxiolytic medication used to treat anxiety disorders. It was widely prescribed before the development of benzodiazepines. Its use has declined due to the availability of newer medications, but it remains a part of the history of psychotropic drugs.
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V. Legal Information
Meprobamate, an anxiolytic drug, is classified as a controlled substance in some jurisdictions due to its potential for abuse. Its status reflects efforts to manage its use and prevent misuse.
US Federal Schedule - IV
Schedule IV drugs, substances, or chemicals are defined as drugs with a low potential for abuse and low risk of dependence. Some examples of Schedule IV drugs are: Xanax, Soma, Darvon, Darvocet, Valium, Ativan, Talwin, Ambien, Tramadol.
Key US Federal Policies:
Controlled Substances Act. Public Law: Public Law 91-513 (text can be found on GovInfo) (https://www.dea.gov/drug-information/csa). Date enacted: October 27, 1970.
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VI. Physical Effects
Meprobamate is an anxiolytic used to treat anxiety disorders. As a downer, it induces sedation and muscle relaxation. Short-term effects include reduced anxiety and improved relaxation, while long-term use can lead to dependence and tolerance. Overdose risks involve severe sedation and respiratory depression. Safe dosing typically ranges from 400-1200 mg daily. Recent research emphasizes its effectiveness and potential risks of misuse.  |
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VII. Psychological Effects
Meprobamate, an anxiolytic, affects GABA-A receptors, providing sedation and anxiolysis. Immediate effects include reduced anxiety and relaxation, with effects lasting several hours. Long-term use can lead to dependence, cognitive impairments, and mood disturbances. Research indicates risks of cognitive decline and psychological dependence with chronic use.
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VIII. Culture
Meprobamate is an anxiolytic and muscle relaxant, classifying it as a downer. Short-term use relieves anxiety and muscle spasms, while long-term use can lead to dependence and cognitive impairment. Overdose risks include severe sedation, respiratory depression, and potentially fatal outcomes. Safe dosages are typically prescribed by medical professionals. Recent research highlights its effectiveness in anxiety management but warns of addiction risks. Physical effects include drowsiness, impaired coordination, and potential respiratory depression.
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