Name: meta-Fluoroisobutyryl fentanyl (N-(3-fluorophenyl)-N-(1-phenethylpiperidin-4-yl)isobutyramide)
Type: Synthetic opioid
AKA: N/A
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II. Natural Derivative
Synthetic substance, no natural derivative
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III. Chemical Profile (IUPAC name)
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IV. History
Meta-fluoroisobutyryl fentanyl, a synthetic opioid, emerged in the early 2010s as a fentanyl analog. It was developed with modifications to increase its potency and stability. The substance's rise in the illicit drug market reflects a broader trend of creating potent synthetic opioids. Its high potency and association with overdose fatalities have prompted regulatory actions to address its distribution and mitigate its impact on public health.
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V. Legal Information
Meta-Fluoroisobutyryl fentanyl is a synthetic opioid with high abuse potential. In the U.S., it is controlled under the Federal Analog Act due to its similarity to other opioids. Globally, its regulation reflects increasing efforts to manage synthetic opioid misuse. [Source: UNODC].
US Federal Schedule - I
Schedule I drugs, substances, or chemicals are defined as drugs with no currently accepted medical use and a high potential for abuse. Some examples of Schedule I drugs are: heroin, lysergic acid diethylamide (LSD), marijuana (cannabis), 3,4-methylenedioxymethamphetamine (ecstasy), methaqualone, and peyote.
Key US Federal Policies:
Controlled Substances Act. Public Law: Public Law 91-513 (text can be found on GovInfo) (https://www.dea.gov/drug-information/csa). Date enacted: October 27, 1970.
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VI. Physical Effects
Meta-Fluoroisobutyryl Fentanyl, a potent synthetic opioid, emerged in the early 2010s. It acts as a downer, providing strong pain relief and sedation. Physical impacts include significant respiratory depression, decreased heart rate, and constricted pupils. Short-term use is effective for severe pain, but long-term use may lead to addiction, tolerance, and severe respiratory issues. Overdose risks include fatal respiratory depression. Safe use involves precise dosing under medical supervision. Recent research highlights its potency and risks associated with synthetic opioids. |
VII. Psychological Effects
Meta-fluoroisobutyryl fentanyl, a potent opioid, affects mu-opioid receptors, providing strong euphoria and analgesia. Immediate effects include intense mood elevation and sedation, lasting several hours. Long-term use may result in severe addiction, cognitive impairments, and mood disorders. Research highlights its potency and the associated psychological risks of dependence and cognitive effects.
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VIII. Culture
Meta-fluoroisobutyryl fentanyl is a synthetic opioid, classifying it as a downer. Short-term use provides potent analgesic effects, while long-term use can lead to dependence, tolerance, and severe health risks. Overdose risks are extremely high, causing severe respiratory depression and potentially fatal outcomes. Safe dosages are not well-established, with use often limited to controlled medical environments. Recent research emphasizes its high potency and associated risks. Physical effects include drowsiness, constricted pupils, and respiratory depression.
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