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Name: Midazolam
Type: Benzodiazepine
AKA: Versed
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II. Natural Derivative
Synthetic substance, no natural derivative
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IV. History
Midazolam, a benzodiazepine, was introduced in the 1970s. It is used for sedation, anesthesia, and procedural sedation due to its rapid onset and short duration. It is widely used in hospitals and surgical settings for its effectiveness in calming patients before procedures.
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V. Legal Information
Midazolam is a benzodiazepine used for sedation and anesthesia. It is controlled due to its potential for abuse and dependence, with regulations ensuring its safe medical use. [Source: UNODC].
US Federal Schedule - IV
Schedule IV drugs, substances, or chemicals are defined as drugs with a low potential for abuse and low risk of dependence. Some examples of Schedule IV drugs are: Xanax, Soma, Darvon, Darvocet, Valium, Ativan, Talwin, Ambien, Tramadol.
Key US Federal Policies:
Controlled Substances Act. Public Law: Public Law 91-513 (text can be found on GovInfo) (https://www.dea.gov/drug-information/csa). Date enacted: October 27, 1970.
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VI. Physical Effects
Midazolam is a benzodiazepine used for sedation and anesthesia. It causes drowsiness, reduced heart rate, and muscle relaxation. Short-term use provides effective sedation and anesthesia, while long-term use may lead to dependence, cognitive impairment, and withdrawal symptoms. Overdose risks include severe sedation and respiratory depression. Safe use involves careful dosing and monitoring. Recent research emphasizes its effectiveness in procedural sedation and associated risks with prolonged use.  |
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VII. Psychological Effects
Midazolam, a benzodiazepine, affects GABA receptors, leading to sedation and anxiety relief. Immediate effects include mood relaxation and reduced anxiety, lasting several hours. Long-term use may result in cognitive impairments, tolerance, and dependence. Research highlights its efficacy in sedation and the risks of cognitive effects and psychological dependence.
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VIII. Culture
Midazolam is a benzodiazepine used for sedation and anesthesia, classifying it as a downer. Short-term use promotes sedation and amnesia, while long-term use can lead to dependence, tolerance, and cognitive impairment. Overdose risks include severe sedation, respiratory depression, and potentially fatal outcomes. Safe dosages are typically prescribed by medical professionals. Recent research highlights its effectiveness in procedural sedation but warns of potential dependence and overdose risks. Physical effects include drowsiness, impaired coordination, and respiratory depression.
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