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Name: N-(4-methoxyphenyl)-N-(1-phenethylpiperidin-4-yl)butyramide para-Methoxyfuranyl fentanyl (N-(4-methoxyphenyl)-N-(1-phenethylpiperidin-4-yl)furan-2-carboxamide)
Type: Synthetic opioid
AKA: N/A
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II. Natural Derivative
Synthetic substance, no natural derivative
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III. Chemical Profile (IUPAC name)
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IV. History
Para-methoxyfuranyl fentanyl (PMF-F) is a synthetic opioid and analog of fentanyl. It was first identified in the 2010s as part of the growing issue of novel synthetic opioids appearing in the illicit drug market. PMF-F is known for its high potency and associated risk of overdose. Its emergence has contributed to ongoing efforts to regulate and control synthetic opioids to prevent misuse and fatalities.
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V. Legal Information
Para-methoxyfuranyl fentanyl is a synthetic opioid analog, often regulated under analog acts due to its similarity to controlled substances like fentanyl. In the US, it is considered a Schedule I substance if deemed similar to other fentanyl analogs. Internationally, it faces increasing restrictions due to its high potency and associated risks, reflecting global efforts to address the synthetic opioid crisis.
US Federal Schedule - I
Schedule I drugs, substances, or chemicals are defined as drugs with no currently accepted medical use and a high potential for abuse. Some examples of Schedule I drugs are: heroin, lysergic acid diethylamide (LSD), marijuana (cannabis), 3,4-methylenedioxymethamphetamine (ecstasy), methaqualone, and peyote.
Key US Federal Policies:
Controlled Substances Act. Public Law: Public Law 91-513 (text can be found on GovInfo) (https://www.dea.gov/drug-information/csa). Date enacted: October 27, 1970.
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VI. Physical Effects
Para-Methoxyfuranyl fentanyl, a potent synthetic opioid, provides significant pain relief and sedation. As a downer, it can cause respiratory depression, drowsiness, and reduced heart rate. Short-term effects include pain relief and euphoria, while long-term use may result in addiction and overdose. Overdose risks involve severe respiratory issues and potential fatality. Safe use requires careful dosing due to high potency. Recent research focuses on its high abuse potential and the need for stringent control measures.  |
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VII. Psychological Effects
This synthetic opioid affects the brain’s opioid receptors, leading to intense euphoria and pain relief. Psychological effects include altered mood and cognition. Long-term use can result in dependence and significant mental health issues. Recent research focuses on its potency and risks of abuse.
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VIII. Culture
Para-methoxyfuranyl fentanyl, a synthetic opioid, has emerged as a potent and dangerous substance in the ongoing opioid crisis. Its cultural impact is tied to the proliferation of synthetic opioids that contribute to high overdose rates and public health challenges. The substance is part of the broader narrative of the opioid epidemic, highlighting the dangers of synthetic analogs in the illicit drug market. It underscores the complexities of drug regulation and the continuous efforts of law enforcement and public health agencies to combat the spread of dangerous synthetic opioids. The cultural narrative around this substance is one of caution and crisis management.
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