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Name: Noroxymorphone
Type: Opioid
AKA: N/A
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II. Natural Derivative
Synthetic substance, no natural derivative
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III. Chemical Profile (IUPAC name)
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IV. History
Noroxymorphone is a metabolite of oxycodone and oxymorphone, both of which are opioid analgesics. It has been studied for its potential pharmacological effects, though it is not used therapeutically on its own. The presence of noroxymorphone in the body indicates the metabolism of its parent compounds, and it is often monitored in drug testing to detect oxycodone or oxymorphone use.
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V. Legal Information
Noroxymorphone, a metabolite of oxymorphone, is not specifically listed as a controlled substance but may be subject to regulation under analog or general opioid laws. In the US, oxymorphone is classified as a Schedule II drug, and similar controls may apply. Globally, its status varies, with increasing attention to opioids and their metabolites reflecting concerns about abuse and addiction.
US Federal Schedule - II
Schedule II drugs, substances, or chemicals are defined as drugs with a high potential for abuse, with use potentially leading to severe psychological or physical dependence. These drugs are also considered dangerous. Some examples of Schedule II drugs are: combination products with less than 15 milligrams of hydrocodone per dosage unit (Vicodin), cocaine, methamphetamine, methadone, hydromorphone (Dilaudid), meperidine (Demerol), oxycodone (OxyContin), fentanyl, Dexedrine, Adderall, and Ritalin.
Key US Federal Policies:
Controlled Substances Act. Public Law: Public Law 91-513 (text can be found on GovInfo) (https://www.dea.gov/drug-information/csa). Date enacted: October 27, 1970.
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VI. Physical Effects
Noroxymorphone, a metabolite of oxymorphone, is an opioid with similar effects. As a downer, it induces significant sedation and pain relief. Short-term effects include euphoria and drowsiness, while long-term use can lead to dependence and respiratory depression. Overdose risks include severe respiratory failure. Safe use involves careful monitoring of doses. Recent research highlights its role in pain management and potential for abuse.  |
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VII. Psychological Effects
Noroxymorphone, an opioid metabolite, impacts opioid receptors, leading to pain relief and euphoria. Psychological effects include mood alteration and potential cognitive issues. Long-term use carries risks of dependence and significant mental health impacts. Current research focuses on its role in opioid metabolism and safety.
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VIII. Culture
Noroxymorphone, an opioid analgesic and metabolite of oxymorphone, has been used primarily in medical settings for pain management. Its cultural significance is relatively minor compared to more widely known opioids, but it is part of the broader narrative of opioid use and the ongoing challenges of managing pain while preventing abuse. The substance highlights the complexities of opioid pharmacotherapy and the balance between providing effective pain relief and mitigating the risks of dependency and misuse. Noroxymorphone’s role in the cultural narrative is one of many substances contributing to the ongoing discourse on opioid use and regulation.
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