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Name: Ocfentanil
Type: Synthetic opioid
AKA: N/A
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II. Natural Derivative
Synthetic substance, no natural derivative
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III. Chemical Profile (IUPAC name)
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IV. History
Oc-fentanil, a synthetic opioid, was developed in the 1970s as part of research into potent analgesics. It is an analog of fentanyl, designed to be more potent and with a different profile of effects. Oc-fentanil's high potency has made it a focus of concern due to its potential for overdose and addiction. Its use has been primarily in clinical settings under strict regulation, but its appearance in illicit markets has prompted increased scrutiny and regulatory controls.
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V. Legal Information
Ocfentanil is a synthetic opioid with analgesic effects, regulated due to its high potential for abuse. It is controlled under the Federal Analog Act in the U.S. if it mimics other opioids. Globally, its status is similar, with increasing regulation to address the opioid crisis and prevent misuse. [Source: UNODC].
US Federal Schedule - I
Schedule I drugs, substances, or chemicals are defined as drugs with no currently accepted medical use and a high potential for abuse. Some examples of Schedule I drugs are: heroin, lysergic acid diethylamide (LSD), marijuana (cannabis), 3,4-methylenedioxymethamphetamine (ecstasy), methaqualone, and peyote.
Key US Federal Policies:
Controlled Substances Act. Public Law: Public Law 91-513 (text can be found on GovInfo) (https://www.dea.gov/drug-information/csa). Date enacted: October 27, 1970.
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VI. Physical Effects
Ocfentanil is a potent opioid analgesic that causes sedation and pain relief. It leads to constricted pupils, reduced heart rate, and respiratory depression. Short-term use provides strong pain relief, while long-term use may result in addiction and respiratory issues. Overdose risks include fatal respiratory depression. Safe use requires medical oversight. Recent research highlights its potency and the risks associated with opioid use.  |
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VII. Psychological Effects
Ocfentanil, a synthetic opioid, provides intense euphoria, sedation, and pain relief. It affects mu-opioid receptors, leading to immediate mood elevation and significant cognitive impairment. Long-term use can lead to addiction, tolerance, and severe withdrawal symptoms. Chronic use is associated with mood disorders, cognitive decline, and high overdose risk. Recent studies emphasize its potency and the severe psychological impacts of synthetic opioids.
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VIII. Culture
Ocfentanil is a synthetic opioid analgesic, significantly more potent than fentanyl. Its cultural significance lies in its impact on the opioid crisis, particularly its role in overdose deaths. Originally developed for pain management, synthetic opioids like Ocfentanil have led to widespread misuse and significant public health challenges. Historically, opioids have been used for centuries for pain relief and recreational purposes. The modern misuse of potent opioids has led to high-profile overdoses and ongoing debates about drug policy, harm reduction, and the balance between medical necessity and the risk of abuse. Media coverage often highlights the dangers and regulatory challenges associated with such potent substances.
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