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Name: ortho-Fluorobutyryl fentanyl (N-(2-fluorophenyl)-N-(1-phenethylpiperidin-4-yl)butyramide; also known as 2-fluorobutyryl fentanyl)
Type: Synthetic opioid
AKA: N/A
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II. Natural Derivative
Synthetic substance, no natural derivative
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III. Chemical Profile (IUPAC name)
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IV. History
Ortho-fluorobutyryl fentanyl, a synthetic opioid, was developed in the 2010s as a more potent analog of fentanyl. Its introduction reflects a trend towards creating highly potent opioids. Ortho-fluorobutyryl fentanyl's high potency has led to its appearance in the illicit drug market, where it has been associated with increased overdose deaths. Its regulation has become a focus for public health and safety measures.
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V. Legal Information
Ortho-Fluorobutyryl Fentanyl, a potent synthetic opioid, is classified as a Schedule I substance in the US, making it illegal. Its high potential for abuse and overdose risks lead to similar bans in many countries. The UNODC and other regulatory bodies monitor synthetic opioids, emphasizing strict control measures to prevent misuse and address the opioid crisis.
US Federal Schedule - I
Schedule I drugs, substances, or chemicals are defined as drugs with no currently accepted medical use and a high potential for abuse. Some examples of Schedule I drugs are: heroin, lysergic acid diethylamide (LSD), marijuana (cannabis), 3,4-methylenedioxymethamphetamine (ecstasy), methaqualone, and peyote.
Key US Federal Policies:
Controlled Substances Act. Public Law: Public Law 91-513 (text can be found on GovInfo) (https://www.dea.gov/drug-information/csa). Date enacted: October 27, 1970.
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VI. Physical Effects
Ortho-Fluorobutyryl Fentanyl, a synthetic opioid, emerged in the early 2000s as a potent analgesic. It acts as a downer, providing strong pain relief and sedation. Physical impacts include significant respiratory depression, decreased heart rate, and constricted pupils. Short-term use can lead to drowsiness and impaired cognitive function, while long-term use may result in addiction, tolerance, and severe respiratory issues. Overdose risks include fatal respiratory depression. Safe use involves precise dosing under medical supervision. Recent research highlights its potency and the risks associated with synthetic opioids.  |
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VII. Psychological Effects
Ortho-fluorobutyryl fentanyl, an opioid, affects opioid receptors, causing euphoria and cognitive impairment. Immediate effects include mood enhancement and pain relief, while long-term use can result in dependence and psychological issues such as depression. Effects last several hours, with significant mental health risks with chronic use.
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VIII. Culture
Ortho-Fluorobutyryl Fentanyl is a synthetic opioid with no historical or cultural lore, emerging in recent years. Its cultural significance is tied to discussions about synthetic opioids, their regulation, and their impact on public health. Proponents of strict regulation highlight its potential for abuse and overdose, while some argue for its controlled medical use. Its primary impact is seen in the context of the opioid epidemic, reflecting broader societal challenges in managing synthetic opioid proliferation.
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