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Name: ortho-Fluorofuranyl fentanyl (N-(2-fluorophenyl)-N-(1-phenethylpiperidin-4-yl)furan-2-carboxamide)
Type: Synthetic opioid
AKA: N/A
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II. Natural Derivative
Synthetic substance, no natural derivative
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III. Chemical Profile (IUPAC name)
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IV. History
Ortho-fluorofuranyl fentanyl, a synthetic opioid, was first synthesized in the 2010s. It is a fentanyl analog designed to enhance potency and stability compared to fentanyl. The substance's introduction to the illicit drug market is part of a broader trend of developing new synthetic opioids. Ortho-fluorofuranyl fentanyl's potent effects and association with overdose deaths have led to increased regulatory measures to control its distribution and mitigate health risks.
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V. Legal Information
Ortho-fluorofuranyl fentanyl, a synthetic opioid, is classified as a Schedule I substance in the US, making it illegal. Many countries have similar bans due to its high potency and risk of overdose. The UNODC highlights the dangers of synthetic opioids, leading to increased international efforts to regulate and control their distribution and use.
US Federal Schedule - I
Schedule I drugs, substances, or chemicals are defined as drugs with no currently accepted medical use and a high potential for abuse. Some examples of Schedule I drugs are: heroin, lysergic acid diethylamide (LSD), marijuana (cannabis), 3,4-methylenedioxymethamphetamine (ecstasy), methaqualone, and peyote.
Key US Federal Policies:
Controlled Substances Act. Public Law: Public Law 91-513 (text can be found on GovInfo) (https://www.dea.gov/drug-information/csa). Date enacted: October 27, 1970.
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VI. Physical Effects
Ortho-fluorofuranyl fentanyl is a synthetic opioid with potent analgesic effects. It acts as a downer, causing sedation and respiratory depression. Short-term use is effective for pain management, but long-term use can lead to addiction, tolerance, and severe health issues. Overdose risks include fatal respiratory depression. Safe use requires strict dosing and medical supervision. Recent research focuses on its potency and risks compared to other opioids.  |
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VII. Psychological Effects
A potent fentanyl analog causing strong analgesia and euphoria. Long-term use can lead to addiction, cognitive impairments, and mood disorders. Research emphasizes its impact on opioid receptors and associated psychological risks.
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VIII. Culture
Ortho-fluorofuranyl fentanyl is a potent synthetic opioid, classifying it as a downer. Short-term use provides effective pain relief, while long-term use can lead to dependence and tolerance. Overdose risks are extremely high, causing respiratory depression and potentially fatal outcomes. Safe dosages are strictly prescribed, often in microgram quantities. Recent research emphasizes its high potency and associated risks of misuse. Physical effects include drowsiness, constricted pupils, and respiratory depression.
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