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Name: ortho-Methyl methoxyacetyl fentanyl (2-methoxy-N-(2-methylphenyl)-N-(1-phenethylpiperidin-4-yl)acetamide)
Type: Synthetic opioid
AKA: 2-methyl methoxyacetyl fentanyl
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II. Natural Derivative
Synthetic substance, no natural derivative
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III. Chemical Profile (IUPAC name)
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IV. History
Ortho-Methyl Methoxyacetyl Fentanyl, a synthetic opioid, emerged in the 2010s. It is known for its strong analgesic effects and is part of a series of fentanyl analogs. Its history is marked by concerns over its potency and the challenges in managing synthetic opioids.
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V. Legal Information
Ortho-Methyl Methoxyacetyl Fentanyl is a synthetic opioid with significant abuse potential. It is classified as a Schedule I controlled substance in the United States and similarly regulated worldwide to prevent misuse and protect public health. [Source: UNODC].
US Federal Schedule - I
Schedule I drugs, substances, or chemicals are defined as drugs with no currently accepted medical use and a high potential for abuse. Some examples of Schedule I drugs are: heroin, lysergic acid diethylamide (LSD), marijuana (cannabis), 3,4-methylenedioxymethamphetamine (ecstasy), methaqualone, and peyote.
Key US Federal Policies:
Controlled Substances Act. Public Law: Public Law 91-513 (text can be found on GovInfo) (https://www.dea.gov/drug-information/csa). Date enacted: October 27, 1970.
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VI. Physical Effects
Ortho-methyl methoxyacetyl fentanyl is a synthetic opioid with potent analgesic effects. It causes sedation, respiratory depression, and constricted pupils. Short-term use is effective for pain management, but long-term use can lead to addiction, tolerance, and severe health issues. Overdose risks include fatal respiratory depression. Safe use involves strict dosing and medical supervision. Recent research highlights its potency and risks compared to other opioids.  |
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VII. Psychological Effects
Ortho-methyl methoxyacetyl fentanyl, a synthetic opioid, interacts with mu-opioid receptors, leading to significant euphoria and sedation. Immediate effects include mood elevation and pain relief, lasting several hours. Long-term use may result in severe addiction, cognitive impairments, and mood disturbances. Research emphasizes its potency and associated risks of psychological dependence.
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VIII. Culture
Ortho-methyl methoxyacetyl fentanyl is a potent synthetic opioid, classifying it as a downer. Short-term use provides effective pain relief, while long-term use can lead to dependence and tolerance. Overdose risks are extremely high, causing respiratory depression and potentially fatal outcomes. Safe dosages are strictly prescribed, often in microgram quantities. Recent research highlights its high potency and associated health risks. Physical effects include drowsiness, constricted pupils, and respiratory depression.
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