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Name: Pentylone
Type: Synthetic cathinone
AKA: ['bk-MBDP; 1-(1', "3-benzodioxol-5-yl)-2-(methylamino)pentan-1-one) (Positional Isomers: dibutylone (bk-DMBDB) and propylone (3'", "4'-methylenedioxy-N-propylaminocathinone; 1-(benzo[d][1", '3]dioxol-5-yl)-2-(propylamino)propan-1-one); 2', '3-methylenedioxy-alpha-ethylaminobutiophenone)']
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II. Natural Derivative
Synthetic substance, no natural derivative
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III. Chemical Profile (IUPAC name)
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IV. History
Pentylone, a synthetic stimulant, was first synthesized in the 1960s but gained attention in the 2000s as a designer drug. It is a member of the substituted cathinone family and is known for its stimulant and empathogenic effects. Its use in recreational settings has led to regulatory measures to control its distribution and use.
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V. Legal Information
Pentylone, a synthetic stimulant, is often regulated under analog laws due to its potential for abuse. In the US, it might be covered under the Federal Analog Act if deemed similar to other controlled substances. Globally, its legal status is restrictive, reflecting efforts to control novel psychoactive substances.
US Federal Schedule - I
Schedule I drugs, substances, or chemicals are defined as drugs with no currently accepted medical use and a high potential for abuse. Some examples of Schedule I drugs are: heroin, lysergic acid diethylamide (LSD), marijuana (cannabis), 3,4-methylenedioxymethamphetamine (ecstasy), methaqualone, and peyote.
Key US Federal Policies:
Controlled Substances Act. Public Law: Public Law 91-513 (text can be found on GovInfo) (https://www.dea.gov/drug-information/csa). Date enacted: October 27, 1970.
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VI. Physical Effects
Pentylone, a synthetic stimulant, induces increased energy and euphoria. As an upper, it raises heart rate and blood pressure. Short-term effects include enhanced alertness and mood, while long-term use may lead to psychological issues. Overdose risks involve severe agitation and cardiovascular problems. Safe dosing varies, and recent findings emphasize its stimulant effects and potential for misuse.  |
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VII. Psychological Effects
Pentylone, a stimulant, impacts dopamine and norepinephrine systems, leading to increased alertness and euphoria. Immediate effects include heightened mood and cognition, while long-term use may cause dependence and cognitive issues. Research highlights its stimulant properties and potential for abuse.
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VIII. Culture
Pentylone, a synthetic cathinone, is part of the new psychoactive substances (NPS) group, often used recreationally for its stimulant and empathogenic effects. Synthetic cathinones have been linked to the 'bath salts' scare in the early 2010s, leading to widespread media attention and legislative action. Historically, natural cathinones are derived from the khat plant, chewed in East African and Arabian cultures for their stimulant effects. Modern use of synthetic variants like pentylone is typically seen in nightlife and festival settings. The substance has sparked debates on public health and safety, as well as the challenge of regulating constantly evolving NPS.
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