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Name: Petrichloral
Type: Sedative-hypnotic
AKA: Pentaerythritol chloral, Periclor
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II. Natural Derivative
Synthetic substance, no natural derivative
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IV. History
Petrichloral, a sedative and hypnotic, was first introduced in the early 1900s. It was developed for its calming effects and was used in the treatment of anxiety and insomnia. The compound's introduction reflected early research into sedative-hypnotic medications. Petrichloral's use has declined due to safety concerns, leading to reduced clinical application.
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V. Legal Information
Petrichloral, a sedative-hypnotic drug, is not widely used or approved for medical use in many countries, including the US. Its legal status varies, with some countries classifying it under controlled substances. Historical use has declined due to the availability of safer alternatives. Regulatory trends focus on restricting obsolete and potentially harmful sedatives.
US Federal Schedule - IV
Schedule IV drugs, substances, or chemicals are defined as drugs with a low potential for abuse and low risk of dependence. Some examples of Schedule IV drugs are: Xanax, Soma, Darvon, Darvocet, Valium, Ativan, Talwin, Ambien, Tramadol.
Key US Federal Policies:
Controlled Substances Act. Public Law: Public Law 91-513 (text can be found on GovInfo) (https://www.dea.gov/drug-information/csa). Date enacted: October 27, 1970.
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VI. Physical Effects
Petrichloral is a barbiturate derivative that acts as a sedative. It induces drowsiness and reduces heart rate. Short-term effects include effective sedation, while long-term use may lead to dependence and cognitive issues. Overdose risks involve severe sedation and respiratory depression. Safe use requires careful medical dosing. Recent research focuses on its efficacy as a sedative and the risks associated with barbiturate use.  |
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VII. Psychological Effects
Petrichloral is a sedative-hypnotic with effects similar to chloral hydrate. It induces sedation, reduced anxiety, and drowsiness. Immediate effects include mood stabilization and sleep induction. Long-term use can lead to dependence, tolerance, and withdrawal symptoms. Chronic use is associated with cognitive impairment and potential development of depressive disorders.
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VIII. Culture
Petrichloral is a sedative and hypnotic drug, historically used to treat insomnia. The use of sedatives reflects societal approaches to managing sleep disorders and the importance placed on rest and recovery. Petrichloral's cultural significance lies in its representation of early pharmacological efforts to address insomnia, a common and often debilitating condition. The history of sedatives involves the evolution of sleep aids and the ongoing search for safe and effective treatments. Media discussions about sleep medications often highlight personal stories and the challenges of balancing efficacy with the risk of dependence, underscoring broader concerns about mental health and well-being.
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