|
Name: Phentermine
Type: Stimulant
AKA: N/A
|
|
II. Natural Derivative
Synthetic substance, no natural derivative
 |
|
III. Chemical Profile (IUPAC name)
|
|
IV. History
The discovery of phentermine was made in 1954 by Dr. Allan B. Berman at the University of Pennsylvania. The drug, which is known as amphetamine, is a stimulant that acts on the central nervous system. It was initially marketed as an appetite suppressant for people who were obese. Phentermine was originally manufactured by the American Cyanamid Company.
In the late 1950s, the drug was approved for the treatment of obesity. The FDA was originally against the drug because of the high rate of addiction. In 1960, the FDA changed its position and approved the drug.
The drug has been used to treat people with anorexia and bulimia.
In the 1960s, phentermine was used to treat people who were obese.
The drug was first introduced to the public in 1963 and was approved by the FDA in 1965.
In the late 1970s, phentermine was used to treat people who were obese
|
|
V. Legal Information
Phentermine, a stimulant used for weight loss, is classified as a Schedule IV controlled substance in the US, allowing limited medical use. It is similarly regulated in many countries due to its potential for abuse and health risks. The UNODC monitors stimulants, emphasizing the need for balanced regulation to ensure safe medical use while preventing misuse.
US Federal Schedule - IV
Schedule IV drugs, substances, or chemicals are defined as drugs with a low potential for abuse and low risk of dependence. Some examples of Schedule IV drugs are: Xanax, Soma, Darvon, Darvocet, Valium, Ativan, Talwin, Ambien, Tramadol.
Key US Federal Policies:
Controlled Substances Act. Public Law: Public Law 91-513 (text can be found on GovInfo) (https://www.dea.gov/drug-information/csa). Date enacted: October 27, 1970.
|
|
VI. Physical Effects
Phentermine is an appetite suppressant used for weight loss. It can cause increased heart rate, blood pressure, and restlessness. Short-term effects include effective appetite suppression, while long-term use may lead to cardiovascular issues and dependence. Overdose risks involve severe cardiovascular problems and agitation. Safe dosing requires careful monitoring. Recent research focuses on its efficacy in weight management and potential risks of misuse.  |
|
VII. Psychological Effects
Phentermine, a stimulant, affects norepinephrine and dopamine systems, leading to increased alertness and mood enhancement. Immediate effects include improved mood and appetite suppression, lasting several hours. Long-term use may result in cognitive impairments, mood swings, and potential dependence. Research highlights its stimulant effects and associated risks of psychological dependence and mental health issues.
 |
|
VIII. Culture
Phentermine is an appetite suppressant used for weight loss. It reflects societal attitudes towards body image, health, and the medical management of obesity. Historically, weight loss medications have been developed to address the growing issue of obesity, with varying degrees of success and controversy. Phentermine's cultural significance lies in its representation of the ongoing struggle with weight management and the complexities of balancing efficacy with potential side effects. Media discussions often focus on personal success stories, the challenges of maintaining weight loss, and the broader societal pressures related to body image and health.
 |