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Name: Pregabalin
Type: Anticonvulsant
AKA: Lyrica
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II. Natural Derivative
Synthetic substance, no natural derivative
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III. Chemical Profile (IUPAC name)
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IV. History
Pregabalin, developed in the early 2000s, is used to treat neuropathic pain and epilepsy. It is a significant advancement in the treatment of nerve pain and anxiety disorders. Pregabalin's development has improved patient care for conditions previously difficult to manage.
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V. Legal Information
Pregabalin, used for neuropathic pain and epilepsy, is classified as a controlled substance in some jurisdictions due to its potential for abuse. Its status reflects regulations aimed at managing its use and preventing misuse.
US Federal Schedule - V
Schedule V drugs, substances, or chemicals are defined as drugs with lower potential for abuse than Schedule IV and consist of preparations containing limited quantities of certain narcotics. Schedule V drugs are generally used for antidiarrheal, antitussive, and analgesic purposes. Some examples of Schedule V drugs are: cough preparations with less than 200 milligrams of codeine or per 100 milliliters (Robitussin AC), Lomotil, Motofen, Lyrica, Parepectolin.
Key US Federal Policies:
Controlled Substances Act. Public Law: Public Law 91-513 (text can be found on GovInfo) (https://www.dea.gov/drug-information/csa). Date enacted: October 27, 1970.
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VI. Physical Effects
Pregabalin is used for neuropathic pain and anxiety. It acts as a downer, reducing pain and anxiety. Short-term use is effective for managing these conditions, but long-term use may lead to dependence and cognitive issues. Overdose risks include severe sedation and potential respiratory issues. Safe use involves prescribed dosing. Recent research highlights its effectiveness and safety profile in treating neuropathic pain and anxiety.  |
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VII. Psychological Effects
Pregabalin, used for neuropathic pain and anxiety, affects neurotransmitter release. Immediate effects include pain relief and mood improvement, with long-term use potentially causing dependence and cognitive impairments. Research explores its efficacy and safety in treating neuropathic pain and anxiety.
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VIII. Culture
Pregabalin is an anticonvulsant and anxiolytic used for neuropathic pain, epilepsy, and anxiety disorders, classifying it as neither an upper nor a downer. Short-term use reduces pain and anxiety, while long-term use can lead to dependence. Overdose risks include severe respiratory depression and potentially fatal outcomes. Safe dosages are medically prescribed, typically under 600 mg per day. Recent research supports its efficacy in pain and anxiety management but warns of addiction risks. Physical effects include dizziness, drowsiness, and reduced pain.
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