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Name: Secobarbital suppository dosage form
Type: Barbiturate
AKA: N/A
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II. Natural Derivative
Synthetic substance, no natural derivative
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III. Chemical Profile (IUPAC name)
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IV. History
Secobarbital, a barbiturate, has been used since the 1930s as a sedative and hypnotic. It is known for its role in the treatment of insomnia and anxiety. The suppository form was developed to provide alternative administration routes, especially for patients who cannot take oral medications.
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V. Legal Information
Secobarbital, a barbiturate used for sedation, is classified as a controlled substance in many jurisdictions. Its status reflects regulations aimed at managing its use and preventing misuse.
US Federal Schedule - III
Schedule III drugs, substances, or chemicals are defined as drugs with a moderate to low potential for physical and psychological dependence. Schedule III drugs abuse potential is less than Schedule I and Schedule II drugs but more than Schedule IV. Some examples of Schedule III drugs are: products containing less than 90 milligrams of codeine per dosage unit (Tylenol with codeine), ketamine, anabolic steroids, testosterone.
Key US Federal Policies:
Controlled Substances Act. Public Law: Public Law 91-513 (text can be found on GovInfo) (https://www.dea.gov/drug-information/csa). Date enacted: October 27, 1970.
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VI. Physical Effects
Secobarbital is a barbiturate used for its sedative and hypnotic effects. It acts as a downer, causing sedation and impaired motor function. Short-term use is effective for sleep disorders, but long-term use can lead to dependence and cognitive issues. Overdose risks include severe sedation and respiratory depression. Safe use requires careful dosing and medical supervision. Recent research explores its efficacy and safety compared to other sedatives.  |
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VII. Psychological Effects
Secobarbital, a barbiturate, affects GABA-A receptors to provide sedation and mood alteration. Immediate effects include relaxation and cognitive impairment, with long-term use potentially leading to dependence and cognitive decline. Research focuses on its use in sedation and potential psychological impacts.
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VIII. Culture
Secobarbital, in its suppository form, has been used for sedation and sleep disorders. It gained cultural significance in the 20th century for its medical use and controversies. Proponents emphasize its effectiveness in managing sleep and anxiety, while opponents raise concerns about addiction and misuse. Its use is both medicinal and controversial, reflecting broader debates about barbiturate use in medicine.
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