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Name: Sufentanil
Type: Opioid
AKA: Sufenta
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II. Natural Derivative
Synthetic substance, no natural derivative
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III. Chemical Profile (IUPAC name)
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IV. History
Sufentanil, a potent opioid analgesic, was developed in the 1970s by Janssen Pharmaceutica. It is used for its rapid onset and high potency in surgical and intensive care settings. Sufentanil has become an important drug in pain management due to its effectiveness and precision in controlling severe pain.
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V. Legal Information
Sufentanil, a potent synthetic opioid, is classified as a Schedule II controlled substance in the US due to its high potential for abuse. Globally, it faces similar restrictions to manage its use in medical settings and prevent misuse.
US Federal Schedule - II
Schedule II drugs, substances, or chemicals are defined as drugs with a high potential for abuse, with use potentially leading to severe psychological or physical dependence. These drugs are also considered dangerous. Some examples of Schedule II drugs are: combination products with less than 15 milligrams of hydrocodone per dosage unit (Vicodin), cocaine, methamphetamine, methadone, hydromorphone (Dilaudid), meperidine (Demerol), oxycodone (OxyContin), fentanyl, Dexedrine, Adderall, and Ritalin.
Key US Federal Policies:
Controlled Substances Act. Public Law: Public Law 91-513 (text can be found on GovInfo) (https://www.dea.gov/drug-information/csa). Date enacted: October 27, 1970.
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VI. Physical Effects
Sufentanil, a potent opioid analgesic, is used for pain management and anesthesia. As a downer, it induces significant sedation and respiratory depression. Short-term effects include pain relief and euphoria, while long-term use can lead to tolerance and dependence. Overdose risks involve severe respiratory depression and potential fatality. Safe dosing requires precise medical supervision. Recent findings focus on its high potency and clinical use in controlled settings.  |
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VII. Psychological Effects
Sufentanil, a potent opioid, affects opioid receptors to produce intense euphoria and analgesia. Immediate effects include mood swings and cognitive impairment, with long-term use carrying risks of dependence and severe mental health issues. Research examines its potency and abuse potential.
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VIII. Culture
Sufentanil, an extremely potent synthetic opioid, is used primarily in surgical settings for pain management. Its potency has made it a critical tool in anesthesiology, but also a substance of concern for potential misuse. Historically, opioids have been central to pain management, from opium use in ancient cultures to modern pharmaceuticals. Sufentanil's use is restricted to medical professionals, but it represents the broader opioid crisis' issues, highlighting the balance between medical necessity and abuse potential. Discussions about sufentanil often intersect with broader debates about opioid prescribing practices and the need for effective pain management solutions.
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