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Name: Tetrahydrocannabinols
Type: Cannabinoid
AKA: THC, Delta-8 THC, Delta-9 THC, dronabinol and others
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II. Natural Derivative
Synthetic substance, no natural derivative
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III. Chemical Profile (IUPAC name)
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IV. History
Tetrahydrocannabinol (THC) was first isolated in the 1960s by Raphael Mechoulam. It is the primary psychoactive compound in cannabis and is widely studied for its effects on the human brain. THC's introduction marked significant milestones in cannabis research and its eventual use in medical treatments, including pain management and appetite stimulation. Its legal status and cultural impact have evolved, reflecting ongoing debates about cannabis use and legalization.
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V. Legal Information
Tetrahydrocannabinols (THC), the active compounds in cannabis, have varying legal statuses worldwide. In the US, THC is classified as a Schedule I controlled substance federally, but several states have legalized cannabis for medical and recreational use. Countries like Canada and Uruguay have fully legalized it. The UNODC calls for balanced policies to prevent abuse while allowing medical research. Trends show a global shift towards legalization.
US Federal Schedule - I
Schedule I drugs, substances, or chemicals are defined as drugs with no currently accepted medical use and a high potential for abuse. Some examples of Schedule I drugs are: heroin, lysergic acid diethylamide (LSD), marijuana (cannabis), 3,4-methylenedioxymethamphetamine (ecstasy), methaqualone, and peyote.
Key US Federal Policies:
Controlled Substances Act. Public Law: Public Law 91-513 (text can be found on GovInfo) (https://www.dea.gov/drug-information/csa). Date enacted: October 27, 1970.
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VI. Physical Effects
Tetrahydrocannabinols (THCs) are the primary psychoactive compounds in cannabis. They induce euphoria, altered perception, and increased appetite. Short-term effects include relaxation and mood enhancement, while long-term use may lead to dependence and cognitive issues. Overdose risks are minimal but can include paranoia and impaired coordination. Safe use involves moderation. Recent research focuses on their therapeutic benefits and risks of long-term use.  |
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VII. Psychological Effects
Tetrahydrocannabinols (THC), the active component in cannabis, affects the endocannabinoid system, causing euphoria and altered perception. Immediate effects include mood enhancement and cognitive impairment, lasting several hours. Long-term use can lead to psychological issues such as anxiety and cognitive decline. Research indicates significant mental health risks with chronic use, including potential for addiction and severe mood disturbances.
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VIII. Culture
Tetrahydrocannabinols (THCs) are the psychoactive compounds found in cannabis. The history of cannabis use spans thousands of years, from ancient medicinal and recreational use to its contemporary legalization and regulation. THCs' cultural significance is immense, reflecting evolving attitudes towards cannabis, its medicinal benefits, and its recreational use. Media coverage often focuses on the legalization movement, the potential health benefits and risks, and the societal impact of cannabis use. The cultural narrative of THCs includes discussions about criminal justice, public health, and the balance between regulation and personal freedom.
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