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Name: Thiopental
Type: Barbiturate
AKA: Pentothal
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II. Natural Derivative
Synthetic substance, no natural derivative
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III. Chemical Profile (IUPAC name)
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IV. History
Thiopental, a barbiturate, was developed in the 1930s. It is used for anesthesia induction and has been a staple in surgical procedures. It has largely been replaced by newer anesthetics but remains a significant part of anesthesia history.
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V. Legal Information
Thiopental is a barbiturate used as an anesthetic. It is controlled due to its potential for abuse and dependence, with regulations ensuring safe medical use. [Source: UNODC].
US Federal Schedule - III
Schedule III drugs, substances, or chemicals are defined as drugs with a moderate to low potential for physical and psychological dependence. Schedule III drugs abuse potential is less than Schedule I and Schedule II drugs but more than Schedule IV. Some examples of Schedule III drugs are: products containing less than 90 milligrams of codeine per dosage unit (Tylenol with codeine), ketamine, anabolic steroids, testosterone.
Key US Federal Policies:
Controlled Substances Act. Public Law: Public Law 91-513 (text can be found on GovInfo) (https://www.dea.gov/drug-information/csa). Date enacted: October 27, 1970.
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VI. Physical Effects
Thiopental is a barbiturate used for anesthesia and sedation. It causes profound sedation, reduced heart rate, and constricted pupils. Short-term use induces anesthesia for surgical procedures, while long-term use can lead to dependence and cognitive impairment. Overdose risks include severe respiratory depression and potential death. Safe use involves careful dosing and monitoring. Recent research focuses on its historical use in anesthesia and current limitations due to side effects.  |
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VII. Psychological Effects
N/A
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VIII. Culture
Thiopental is a barbiturate used for anesthesia and sedation. Its cultural significance is tied to its historical use in medical procedures and its role in the development of anesthesia practices. Media coverage often discusses its use in medical settings and the challenges associated with barbiturate use. Thiopental is used medicinally and is part of discussions about anesthesia, sedation, and the evolution of medical practices.
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