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Name: UR-144 (1-Pentyl-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)metanone
Type: Synthetic cannabinoid
AKA: UR-144
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II. Natural Derivative
Synthetic substance, no natural derivative
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IV. History
UR-144, a synthetic cannabinoid, was first synthesized in the early 2010s. It was developed as part of research into novel cannabinoid receptor ligands. UR-144 is known for its psychoactive effects similar to THC, the active component in cannabis. It was used in synthetic cannabis products, often marketed as 'legal highs' or 'herbal incense.' Its rapid emergence in the drug market led to health concerns and legal scrutiny. Due to its potent effects and potential for abuse, UR-144 has been banned in many countries. Its history reflects broader trends in the regulation of synthetic cannabinoids and the challenges associated with new psychoactive substances.
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V. Legal Information
UR-144 is a synthetic cannabinoid with psychoactive properties, controlled under analog laws due to its similarity to THC. In the U.S., it is regulated under the Federal Analog Act, making its use and distribution illegal if it mimics controlled substances. Globally, many countries have placed UR-144 under control to address synthetic cannabinoid abuse. [Source: UNODC].
US Federal Schedule - I
Schedule I drugs, substances, or chemicals are defined as drugs with no currently accepted medical use and a high potential for abuse. Some examples of Schedule I drugs are: heroin, lysergic acid diethylamide (LSD), marijuana (cannabis), 3,4-methylenedioxymethamphetamine (ecstasy), methaqualone, and peyote.
Key US Federal Policies:
Controlled Substances Act. Public Law: Public Law 91-513 (text can be found on GovInfo) (https://www.dea.gov/drug-information/csa). Date enacted: October 27, 1970.
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VI. Physical Effects
UR-144 is a synthetic cannabinoid with psychoactive effects. It acts as an upper, producing euphoria and altered perception. Short-term use can lead to intense effects, while long-term impacts are not well documented. Overdose risks include severe psychological effects and potential toxicity. Safe use is uncertain due to limited research. Recent studies focus on its psychoactive properties and health risks.  |
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VII. Psychological Effects
UR-144 is a synthetic cannabinoid producing euphoria, altered perception, and anxiety. Immediate impacts include paranoia, hallucinations, and cognitive impairment. Long-term use can lead to dependence, severe psychiatric disorders, and cognitive deficits. Recent research indicates higher risks of severe anxiety and psychotic episodes compared to natural cannabinoids.
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VIII. Culture
UR-144 is a synthetic cannabinoid used recreationally for its psychoactive effects. It has no significant historical or cultural lore, given its recent development in the early 21st century. Its use is largely underground, popular among those seeking legal alternatives to cannabis. Its association with synthetic drug culture highlights conflicts between proponents advocating for legal highs and opponents concerned about safety and regulation. Celebrities and key figures generally avoid endorsement due to its controversial status. Its cultural significance lies in debates over synthetic versus natural substances and the challenges of regulating designer drugs.
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