Name: Zuranolone
Type: Neurosteroid
AKA: ZURZUVAE
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II. Natural Derivative
Synthetic substance, no natural derivative
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IV. History
Zuranolone, a synthetic steroid, was developed in the 21st century. It is used for its potential antidepressant effects and is studied for its impact on mood disorders and mental health.
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V. Legal Information
Zuranolone, a novel GABA receptor modulator, is currently under investigation for its use in treating major depressive disorder and postpartum depression. It is not yet approved for medical use in the US or other countries. Regulatory bodies like the FDA are closely monitoring its clinical trials. The UNODC has not yet classified this substance. As of now, there are no significant trends or policies regarding its legalization or criminalization.
US Federal Schedule - IV
Schedule IV drugs, substances, or chemicals are defined as drugs with a low potential for abuse and low risk of dependence. Some examples of Schedule IV drugs are: Xanax, Soma, Darvon, Darvocet, Valium, Ativan, Talwin, Ambien, Tramadol.
Key US Federal Policies:
Controlled Substances Act. Public Law: Public Law 91-513 (text can be found on GovInfo) (https://www.dea.gov/drug-information/csa). Date enacted: October 27, 1970.
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VI. Physical Effects
Zuranolone is a neuroactive steroid used for its antidepressant and anxiolytic effects. It acts as a downer, reducing anxiety and improving mood. Short-term use is effective for managing mood disorders, but long-term use may have unknown risks. Overdose risks are low, but excessive use can impair cognitive and motor functions. Safe use requires medical supervision. Recent research focuses on its potential benefits for mood disorders. |
VII. Psychological Effects
Zuranolone, a neuroactive steroid, affects GABA receptors, leading to mood stabilization and anxiety relief. Immediate effects include mood improvement and reduced anxiety, lasting several hours. Long-term use may contribute to overall mental well-being. Research highlights its potential benefits for mood disorders and cognitive effects through its interaction with neurotransmitter systems.
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VIII. Culture
Zuranolone is a novel medication used in the treatment of depression, particularly postpartum depression. It has no historical or cultural lore, being a recent development. Its modern cultural significance lies in its potential as a breakthrough treatment for depression. Proponents include medical professionals and patients advocating for new, effective treatments for mental health conditions. Opponents may caution about unknown long-term effects and accessibility. Its use is strictly medicinal, reflecting ongoing advancements in psychopharmacology and mental health treatment.
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